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-Structure paper
Title | Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range |
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Journal, issue, pages | Plos Pathog., Year 2023 |
Publish date | Aug 5, 2022 (structure data deposition date) |
![]() | Ni D / Turelli P / Beckert B / Nazarov S / Uchikawa E / Myasnikov A / Pojer F / Trono D / Stahlberg H / Lau K |
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Methods | EM (single particle) |
Resolution | 2.89 - 4.4 Å |
Structure data | ![]() EMDB-15541: Beta SARS-CoV-2 Spike bound to mouse ACE2 (two up, full) ![]() EMDB-15580: BA.1 SARS-CoV-2 Spike bound to mouse ACE2 (two up, full) ![]() EMDB-15581: BA.1 SARS-CoV-2 Spike bound to mouse ACE2 (three up, full) ![]() EMDB-15584: BA.2.12.1 SARS-CoV-2 Spike bound to mouse ACE2 (two up, full) ![]() EMDB-15585: BA.2.12.1 SARS-CoV-2 Spike bound to mouse ACE2 (three up, full) ![]() EMDB-15586: BA.4/5 SARS-CoV-2 Spike bound to mouse ACE2 (two up, full) ![]() EMDB-15587: BA.4/5 SARS-CoV-2 Spike bound to human ACE2 (three up, full) ![]() EMDB-15592: BA.4/5 SARS-CoV-2 Spike bound to mouse ACE2 (local) |
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