タイトル | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom. |
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ジャーナル・号・ページ | Int J Mol Sci, Vol. 24, Year 2023 |
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掲載日 | 2023年3月3日 (構造データの登録日) |
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著者 | Qin, T. / Hu, B. / Zhao, Q. / Wang, Y. / Wang, S. / Luo, D. / Lyu, J. / Chen, Y. / Gan, J. / Huang, Z. |
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リンク | Int J Mol Sci / PubMed:37958741 |
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手法 | X線回折 |
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解像度 | 1.805 - 3 Å |
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構造データ | PDB-8ild: The crystal structure of native dGTP:DNApre-I:Pol X substrate ternary complex 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-8ile: The crystal structure of dGTPalphaSe-Rp:DNApre-II:Pol X substrate ternary complex 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-8ilf: The crystal structure of dGTPalphaSe-Sp:DNApre-II:Pol X substrate ternary complex 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-8ilg: The crystal structure of dG-DNA:Pol X product binary complex 手法: X-RAY DIFFRACTION / 解像度: 1.805 Å PDB-8ilh: The crystal structure of dG(Se-Sp)-DNA:Pol X product binary complex 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-8ili: The crystal structure of dG(Se-Rp)-DNA:Pol X product binary complex 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å |
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化合物 | ChemComp-7Q6: [[(2R,3S,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-selanyl-phosphoryl] phosphono hydrogen phosphate
ChemComp-8EB: [[(2R,3S,5R)-5-(2-azanyl-6-oxidanylidene-3H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-selanyl-phosphoryl] dihydrogen phosphate
ChemComp-GMS: 2'-DEOXYGUANOSINE-5'-MONOSELENOPHOSPHATE
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由来 | african swine fever virus (strain badajoz 1971 vero-adapted) (ウイルス)- synthetic construct (人工物)
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キーワード | REPLICATION/DNA / DNA polymerase / substrate complex / REPLICATION-DNA complex / selenium-modified dNTP / configuration / dNTPalphaSe |
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