EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition.
ジャーナル・号・ページ	Febs Lett., Vol. 597, Page 1770-1778, Year 2023
掲載日	2023年1月13日 (構造データの登録日)
著者	Nakamura, T. / Koga-Ogawa, Y. / Fujimiya, K. / Chirifu, M. / Goto, M. / Ikemizu, S. / Nakabeppu, Y. / Yamagata, Y.
リンク	Febs Lett. / PubMed:36914375
手法	X線回折
解像度	1.05 - 1.48 Å
構造データ	PDB-8i18: Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 7.7 手法: X-RAY DIFFRACTION / 解像度: 1.1 Å PDB-8i19: Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 8.0 手法: X-RAY DIFFRACTION / 解像度: 1.48 Å PDB-8i1a: Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 8.6 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-8i1c: Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 9.1 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-8i1d: Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 7.7 手法: X-RAY DIFFRACTION / 解像度: 1.2 Å PDB-8i1e: Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 8.0 手法: X-RAY DIFFRACTION / 解像度: 1.1 Å PDB-8i1f: Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 8.6 手法: X-RAY DIFFRACTION / 解像度: 1.05 Å PDB-8i1g: Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 9.1 手法: X-RAY DIFFRACTION / 解像度: 1.18 Å PDB-8i1h: Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 9.7 手法: X-RAY DIFFRACTION / 解像度: 1.18 Å PDB-8i1i: Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP at pH 7.7 手法: X-RAY DIFFRACTION / 解像度: 1.2 Å PDB-8i1j: Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP at pH 9.7 手法: X-RAY DIFFRACTION / 解像度: 1.08 Å PDB-8i8s: Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGMP and Mn2+ 手法: X-RAY DIFFRACTION / 解像度: 1.42 Å PDB-8i8t: Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dAMP and Mn2+ 手法: X-RAY DIFFRACTION / 解像度: 1.22 Å
化合物	ChemComp-8DG: 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE / 8-オキソdGTP ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-HOH: WATER ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-6U4: [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate / 2-OH-dATP ChemComp-8OG: 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE / 8-オキソ-dGMP ChemComp-MN: Unknown entry ChemComp-IGU: 2'-DEOXYISOGUANINE-5'-MONOPHOSPHATE
由来	homo sapiens (ヒト)
キーワード	HYDROLASE / Nudix hydrolase