EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity.
ジャーナル・号・ページ	J. Biol. Chem., Vol. 299, Page 102938-102938, Year 2023
掲載日	2022年8月25日 (構造データの登録日)
著者	Chang, C. / Lee Luo, C. / Eleraky, S. / Lin, A. / Zhou, G. / Gao, Y.
リンク	J. Biol. Chem. / PubMed:36702254
手法	X線回折
解像度	1.72 - 2.4 Å
構造データ	PDB-8e85: Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mn2+ 手法: X-RAY DIFFRACTION / 解像度: 1.72 Å PDB-8e86: Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mn2+ 手法: X-RAY DIFFRACTION / 解像度: 1.78 Å PDB-8e87: Human DNA polymerase eta-DNA-rA-ended primer-dGMPNPP ternary mismatch complex with Mg2+ 手法: X-RAY DIFFRACTION / 解像度: 2.19 Å PDB-8e88: Human DNA polymerase eta-DNA-rU-ended primer-dGMPNPP ternary mismatch complex with Mg2+ 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-8e89: Human DNA polymerase eta-DNA-rU-ended primer-binary complex 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-8e8a: Human DNA polymerase eta-DNA-dT-ended primer binary complex 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8e8b: Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-8e8c: Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 30s 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-8e8d: Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 60s 手法: X-RAY DIFFRACTION / 解像度: 2.09 Å PDB-8e8e: Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 90s 手法: X-RAY DIFFRACTION / 解像度: 2.05 Å PDB-8e8f: Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 120s 手法: X-RAY DIFFRACTION / 解像度: 2.14 Å PDB-8e8g: Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 180s 手法: X-RAY DIFFRACTION / 解像度: 2.13 Å PDB-8e8h: Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 300s 手法: X-RAY DIFFRACTION / 解像度: 2.13 Å PDB-8e8j: Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mg2+ 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-8e8k: Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mg2+ 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å
化合物	ChemComp-MN: Unknown entry ChemComp-XG4: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine ChemComp-HOH: WATER ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-DGT: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE / dGTP ChemComp-K: Unknown entry / カリウムカチオン ChemComp-CA: Unknown entry / カルシウムジカチオン ChemComp-DPO: DIPHOSPHATE / ジホスファ-ト
由来	homo sapiens (ヒト) synthetic construct (人工物)
キーワード	TRANSFERASE/DNA / DNA polymerase / TRANSFERASE / TRANSFERASE-DNA complex