EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Evolution-inspired engineering of anthracycline methyltransferases.
ジャーナル・号・ページ	Pnas Nexus, Vol. 2, Page pgad009-pgad009, Year 2023
掲載日	2021年6月17日 (構造データの登録日)
著者	Dinis, P. / Tirkkonen, H. / Wandi, B.N. / Siitonen, V. / Niemi, J. / Grocholski, T. / Metsa-Ketela, M.
リンク	Pnas Nexus / PubMed:36874276
手法	X線回折
解像度	1.51 - 2.77 Å
構造データ	PDB-7owb: Chimeric carminomycin-4-O-methyltransferase (DnrK) with a region from 10-hydroxylase CalMB 手法: X-RAY DIFFRACTION / 解像度: 2.45 Å PDB-7oy1: DnrK mutant RTCR 手法: X-RAY DIFFRACTION / 解像度: 2.39 Å PDB-7pg7: 10-decarboxylase TamK from Streptomyces tsukubaensis 手法: X-RAY DIFFRACTION / 解像度: 1.51 Å PDB-7pga: Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK 手法: X-RAY DIFFRACTION / 解像度: 2.77 Å PDB-7pgj: Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-decarboxylate TamK and 10-hydroxylase RdmB, together with a single point mutation F297G 手法: X-RAY DIFFRACTION / 解像度: 2.13 Å PDB-7phd: Chimeric carminomycin-4-O-methyltransferase (DnrK) with a region from 10-decarboxylase TamK 手法: X-RAY DIFFRACTION / 解像度: 1.53 Å PDB-7phe: Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK 手法: X-RAY DIFFRACTION / 解像度: 2.32 Å PDB-7phf: Chimeric carminomycin-4-O-methyltransferase (DnrK) with regions from 10-hydroxylase RdmB and 10-decarboxylase TamK 手法: X-RAY DIFFRACTION / 解像度: 2.21 Å
化合物	ChemComp-3VL: methyl (1R,2R,4S)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate / アクラシノマイシンT ChemComp-SAH: S-ADENOSYL-L-HOMOCYSTEINE / S-アデノシルホモシステイン ChemComp-HOH: WATER ChemComp-VAK: methyl (1R,2R,4S)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate / アクラビノン ChemComp-ZBX: methyl (1R,2R,4S)-2-ethyl-7-methoxy-2,4,5-tris(oxidanyl)-6,11-bis(oxidanylidene)-3,4-dihydro-1H-tetracene-1-carboxylate ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-SAM: S-ADENOSYLMETHIONINE
由来	streptomyces peucetius (バクテリア) streptomyces sp. zea17i (バクテリア) streptomyces purpurascens (バクテリア) streptomyces tsukubensis (strain dsm 42081 / nbrc 108919 / nrrl 18488 / 9993) (バクテリア) streptomyces tsukubensis (バクテリア)
キーワード	BIOSYNTHETIC PROTEIN / Carminomycin-4-O-methyltransferase variant; Chimeragenesis; aclacinomycin 10-hydroxylase / Carminomycin-4-O-methyltransferase variant; Chimeragenesis; aclacinomycin 10-hydroxylase; komodoquinone 10-decarboxylase; BIOSYNTHETIC PROTEIN / Carminomycin-4-O-methyltransferase variant; Chimeragenesis; tsukubarubicin 10-decarboxylase; Biosynthetic protein / Carminomycin-4-O-methyltransferase variant; Chimeragenesis; aclacinomycin 10-hydroxylase; tsukubarubicin 10-decarboxylase; biosynthetic protein / tsukubarubicin 10-decarboxylase; Biosynthetic protein