タイトル | Chemical probes in the BAZ2A bromodomain |
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ジャーナル・号・ページ | to be published |
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掲載日 | 2021年1月18日 (構造データの登録日) |
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著者 | Cazzanelli, G. / Dalle Vedove, A. / D'Agostino, V.G. / Caflisch, A. / Lolli, G. |
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リンク | PubMedで検索 |
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手法 | X線回折 |
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解像度 | 1.086 - 2.5 Å |
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構造データ | PDB-7bl8: BAZ2A bromodomain in complex with the chemical probe BAZ2-ICR 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-7bl9: BAZ2A bromodomain in complex with GSK2801 chemical probe 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å PDB-7bla: BAZ2A bromodomain in complex with TP-238 chemical probe 手法: X-RAY DIFFRACTION / 解像度: 1.086 Å PDB-7blb: BAZ2A bromodomain in complex with GSK4027 chemical probe 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-7blc: BAZ2A bromodomain in complex with compound UP39 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-7bld: BAZ2A bromodomain in complex with compound UZH23 手法: X-RAY DIFFRACTION / 解像度: 2.35 Å |
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化合物 | ChemComp-WCS: 6-{4-[3-(dimethylamino)propoxy]phenyl}-2-(methylsulfonyl)-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine
ChemComp-9ST: 4-bromo-2-methyl-5-[[(3~{R},5~{R})-1-methyl-5-phenyl-piperidin-3-yl]amino]pyridazin-3-one / GSK-4027
ChemComp-U2E: methyl 5-[(5-ethanoyl-2-ethoxy-phenyl)carbamoyl]-2-(2-piperazin-1-ylethoxy)benzoate
ChemComp-U2K: 1-[3-(6-Methyl-2,3-dihydropyrazolo[5,1-b][1,3]oxazol-7-yl)indol-1-yl]ethanone
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由来 | homo sapiens (ヒト)
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キーワード | TRANSCRIPTION / four helical bundle |
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