EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers.
ジャーナル・号・ページ	Acs Med. Chem. Lett., Vol. 12, Page 976-982, Year 2021
掲載日	2020年12月14日 (構造データの登録日)
著者	Sijbesma, E. / Hallenbeck, K.K. / Andrei, S.A. / Rust, R.R. / Adriaans, J.M.C. / Brunsveld, L. / Arkin, M.R. / Ottmann, C.
リンク	Acs Med. Chem. Lett. / PubMed:34136078
手法	X線回折
解像度	1.1 - 1.7 Å
構造データ	PDB-7b9m: Cys-45-tethered stabilizer 3 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-7b9r: Cys-45-tethered stabilizer 4 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.15 Å PDB-7b9t: Cys-45-tethered stabilizer 5 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.15 Å PDB-7ba3: Cys-42-tethered stabilizer 6 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-7ba5: Cys-42-tethered stabilizer 7 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-7ba6: Cys-42-tethered stabilizer 8 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-7ba7: Cys-42-tethered stabilizer 9 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-7ba8: Cys-42-tethered stabilizer 10 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.2 Å PDB-7ba9: Cys-42-tethered stabilizer 11 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.48 Å PDB-7baa: Cys-42-tethered stabilizer 12 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.1 Å PDB-7bab: Cys-42-tethered stabilizer 13 of 14-3-3(sigma)/ERa PPI 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å
化合物	ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-T4W: 2-(2-cyanophenyl)sulfanyl-~{N}-(2-sulfanylethyl)benzamide ChemComp-HOH: WATER ChemComp-T4Q: 2-(2-cyanophenyl)sulfanyl-~{N}-(3-sulfanylpropyl)benzamide ChemComp-T4Z: 2-(4-chlorophenyl)sulfanyl-~{N}-(3-sulfanylpropyl)ethanamide ChemComp-T5N: 2-(4-bromanylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide ChemComp-T5T: 2-(4-fluoranylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide ChemComp-T5Q: 2-[3,5-bis(fluoranyl)phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide ChemComp-T5W: 2-[3,5-bis(chloranyl)phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide ChemComp-T6H: 2-methyl-2-phenoxy-~{N}-(2-sulfanylethyl)propanamide ChemComp-T6N: 2-methyl-2-(4-methylphenoxy)-~{N}-(2-sulfanylethyl)propanamide ChemComp-T5Z: 2-(4-bromanyl-3-methoxy-phenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide ChemComp-T6W: 2-[2-chloranyl-4-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide
由来	homo sapiens (ヒト)
キーワード	SIGNALING PROTEIN / protein-protein interaction; stabilization; hub protein; transcription factor / protein-protein interaction / stabilizer / hub protein / transcription factor