タイトル | Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization. |
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ジャーナル・号・ページ | Nucleic Acids Res., Vol. 49, Page 646-656, Year 2021 |
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掲載日 | 2019年9月3日 (構造データの登録日) |
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著者 | Zhang, W. / Kim, S.C. / Tam, C.P. / Lelyveld, V.S. / Bala, S. / Chaput, J.C. / Szostak, J.W. |
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リンク | Nucleic Acids Res. / PubMed:33347562 |
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手法 | X線回折 |
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解像度 | 2.36 - 2.95 Å |
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構造データ | PDB-6u7y: RNA hairpin structure containing one TNA nucleotide as template 手法: X-RAY DIFFRACTION / 解像度: 2.95 Å PDB-6u7z: RNA hairpin structure containing one TNA nucleotide as primer 手法: X-RAY DIFFRACTION / 解像度: 2.71 Å PDB-6u89: RNA duplex, bound with TNA monomer 手法: X-RAY DIFFRACTION / 解像度: 2.36 Å PDB-6u8f: RNA hairpin, bound with TNA monomer 手法: X-RAY DIFFRACTION / 解像度: 2.81 Å PDB-6u8u: RNA duplex bound with TNA 3'-3' imidazolium dimer 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å |
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化合物 | ChemComp-TG: 2-azanyl-9-[(2~{R},3~{R},4~{S})-3-oxidanyl-4-[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxy-oxolan-2-yl]-1~{H}-purin-6-one
ChemComp-Q1V: 2-amino-3-[(R)-{[(3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}(hydroxy)phosphoryl]-1-[(S)-{[(3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium
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由来 | - synthetic construct (人工物)
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キーワード | RNA |
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