タイトル | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. |
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ジャーナル・号・ページ | Commun Biol, Vol. 2, Page 240-240, Year 2019 |
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掲載日 | 2018年12月2日 (構造データの登録日) |
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著者 | Ji, C. / Kittredge, A. / Hopiavuori, A. / Ward, N. / Chen, S. / Fukuda, Y. / Zhang, Y. / Yang, T. |
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リンク | Commun Biol / PubMed:31263784 |
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手法 | X線回折 |
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解像度 | 2.45 - 3.8 Å |
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構造データ | PDB-6iv0: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation I180A 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-6iv1: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation I180T 手法: X-RAY DIFFRACTION / 解像度: 3.18 Å PDB-6iv2: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation Y211A 手法: X-RAY DIFFRACTION / 解像度: 2.62 Å PDB-6iv3: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation W252A 手法: X-RAY DIFFRACTION / 解像度: 2.515 Å PDB-6iv4: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation W252F 手法: X-RAY DIFFRACTION / 解像度: 3.14 Å PDB-6ivj: Crystal structure of a membrane protein G18A 手法: X-RAY DIFFRACTION / 解像度: 2.77 Å PDB-6ivk: Crystal structure of a membrane protein G175A 手法: X-RAY DIFFRACTION / 解像度: 2.65 Å PDB-6ivl: Crystal structure of a membrane protein L259A 手法: X-RAY DIFFRACTION / 解像度: 3.4 Å PDB-6ivm: Crystal structure of a membrane protein P143A 手法: X-RAY DIFFRACTION / 解像度: 2.95 Å PDB-6ivn: Crystal structure of a membrane protein G264A 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-6ivo: Crystal structure of a membrane protein P208A 手法: X-RAY DIFFRACTION / 解像度: 2.45 Å PDB-6ivp: Crystal structure of a membrane protein P262A 手法: X-RAY DIFFRACTION / 解像度: 3.8 Å PDB-6ivq: Crystal structure of a membrane protein S19A 手法: X-RAY DIFFRACTION / 解像度: 2.65 Å PDB-6ivr: Crystal structure of a membrane protein W16A 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-6ivw: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation D269A 手法: X-RAY DIFFRACTION / 解像度: 3.72 Å PDB-6jlf: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae D179A mutation - HR 手法: X-RAY DIFFRACTION / 解像度: 2.548 Å |
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化合物 | |
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由来 | - klebsiella pneumoniae is53 (肺炎桿菌)
- klebsiella pneumoniae (肺炎桿菌)
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キーワード | MEMBRANE PROTEIN / Bestrophin-1 / homolog / mutation / klebsiella pneumoniae |
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