タイトル Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects. ジャーナル・号・ページ Org. Biomol. Chem. , Vol. 17, Page 1081-1089, Year 2019掲載日 2018年11月15日 (構造データの登録日) 著者Kumar, R. / Peterson, K. / Misini Ignjatovic, M. / Leffler, H. / Ryde, U. / Nilsson, U.J. / Logan, D.T. リンク Org. Biomol. Chem. / PubMed:30632578手法 X線回折 解像度 0.959 - 1.219 Å 構造データ PDB-6i74 : 構造ビューア Galectin-3C in complex with substituted polyfluoroaryl monothiogalactoside derivative 1 手法 : X-RAY DIFFRACTION / 解像度 : 0.959 Å
PDB-6i75 : 構造ビューア Galectin-3C in complex with substituted polyfluoroaryl monothiogalactoside derivative 2 手法 : X-RAY DIFFRACTION / 解像度 : 1.171 Å
PDB-6i76 : 構造ビューア Galectin-3C in complex with substituted polyfluoroaryl monothiogalactoside derivative-3 手法 : X-RAY DIFFRACTION / 解像度 : 1.2 Å
PDB-6i77 : 構造ビューア Galectin-3C in complex with substituted polyfluoroaryl monothiogalactoside derivative-4 手法 : X-RAY DIFFRACTION / 解像度 : 1.219 Å
PDB-6i78 : 構造ビューア Galectin-3C in complex with substituted polyfluoroaryl monothiogalactoside derivative 5 手法 : X-RAY DIFFRACTION / 解像度 : 1.15 Å
化合物 ChemComp-H5Z : 構造ビューア (2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-4-[4-[2,3,4,5,6-pentakis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol
ChemComp-H5T : 構造ビューア (2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-4-[4-[2,3,5,6-tetrakis(fluoranyl)-4-oxidanyl-phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol
ChemComp-H5N : 構造ビューア (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-[4-azido-2,3,5,6-tetrakis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol
ChemComp-H5Q : 構造ビューア (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-[4-azanyl-2,3,5,6-tetrakis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol
ChemComp-H5H : 構造ビューア (2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-4-[4-[2,3,5,6-tetrakis(fluoranyl)-4-(methylamino)phenyl]-1,2,3-triazol-1-yl]oxane-3,5-diol
由来 homo sapiens (ヒト) キーワード SUGAR BINDING PROTEIN / LECTIN / CARBOHYDRATE-BINDING PROTEIN / GALACTOSE-SPECIFIC LECTIN 3 / GALACTOSIDE-BINDING PROTEIN / GALBP / IGE-6 BINDING PROTEIN / L-31 / LAMININ-BINDING PROTEIN / LECTIN L-29 / MAC-2