タイトル | (ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition. |
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ジャーナル・号・ページ | Cell Chem Biol, Vol. 25, Page 1533-1546.e12, Year 2018 |
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掲載日 | 2018年3月21日 (構造データの登録日) |
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著者 | Rack, J.G.M. / Ariza, A. / Drown, B.S. / Henfrey, C. / Bartlett, E. / Shirai, T. / Hergenrother, P.J. / Ahel, I. |
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リンク | Cell Chem Biol / PubMed:30472116 |
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手法 | X線回折 |
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解像度 | 1.23 - 2.1 Å |
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構造データ | PDB-6g1p: Apo form of ADP-ribosylserine hydrolase ARH3 of Latimeria chalumnae 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-6g1q: ADP-ribosylserine hydrolase ARH3 of Latimeria chalumnae in complex with ADP-ribose 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-6g28: Human [protein ADP-ribosylargenine] hydrolase ARH1 in complex with ADP-ribose 手法: X-RAY DIFFRACTION / 解像度: 1.23 Å PDB-6g2a: Human [protein ADP-ribosylargenine] hydrolase ARH1 in complex with ADP-HPM 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-6hgz: ADP-ribosylserine hydrolase ARH3 of Latimeria chalumnae in complex with ADP-ribose 手法: X-RAY DIFFRACTION / 解像度: 1.86 Å PDB-6hh3: ADP-ribosylserine hydrolase ARH3 of Latimeria chalumnae in complex with ADP-HPD 手法: X-RAY DIFFRACTION / 解像度: 1.82 Å PDB-6hh4: ADP-ribosylserine hydrolase ARH3 of Latimeria chalumnae in complex with ADP-ribosyl-L-arginine 手法: X-RAY DIFFRACTION / 解像度: 1.66 Å PDB-6hh5: ADP-ribosylserine hydrolase ARH3 of Latimeria chalumnae in complex with ADP-HPM 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-6hh6: Human poly(ADP-ribose) glycohydrolase in complex with ADP-HPM 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-6hoz: ADP-ribosylserine hydrolase ARH3 of Latimeria chalumnae in complex with inosine diphosphate ribose (IDPr) 手法: X-RAY DIFFRACTION / 解像度: 1.77 Å |
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化合物 | ChemComp-AR6: [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL
ChemComp-A3R: Adenosine Diphosphate (Hydroxymethyl)pyrrolidine monoalcohol
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由来 | - latimeria chalumnae (シーラカンス)
- homo sapiens (ヒト)
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キーワード | HYDROLASE / ADP-ribosylation / ADP-ribose / ADPRHL2 / ADP-ribosylhydrolase like 2 / ADPRH / ADP-ribosylhydrolase / ARH1 / ADP-HPM / ADP-HPD / Arg-ADPr / Argenine-ADPr / ADP-Ribosyl-L-arginine / PARG / inosine diphosphate ribose / IDPr |
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