EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface.
ジャーナル・号・ページ	Protein Sci., Vol. 27, Page 1810-1820, Year 2018
掲載日	2018年4月25日 (構造データの登録日)
著者	Mesrouze, Y. / Bokhovchuk, F. / Izaac, A. / Meyerhofer, M. / Zimmermann, C. / Fontana, P. / Schmelzle, T. / Erdmann, D. / Furet, P. / Kallen, J. / Chene, P.
リンク	Protein Sci. / PubMed:30058229
手法	X線回折
解像度	1.65 - 2.28 Å
構造データ	PDB-6ge3: X-ray structure of TEAD4 (wildtype) complexed with YAP (wildtype): The role of residual flexibility and water molecules in the adaptation of a bound intrinsically disordered protein to mutations at a binding interface 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-6ge4: TEAD4 (216-434);E263A COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 1.97A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA 手法: X-RAY DIFFRACTION / 解像度: 1.97 Å PDB-6ge5: TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 2.05A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA 手法: X-RAY DIFFRACTION / 解像度: 2.05 Å PDB-6ge6: X-ray structure of TEAD4(E263A+Y429F mutant) complexed with YAP(wildtype): The role of residual flexibility and water molecules in the adaptation of a bound intrinsically disordered protein to mutations at a binding interface 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-6gec: TEAD4 (216-434) COMPLEXED WITH YAP PEPTIDE (60-100);S94A AND MYRISTOATE (COVALENTLY BOUND) AT 1.70A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-6gee: TEAD4 (216-434);E263A COMPLEXED WITH YAP PEPTIDE (60-100); S94A AND MYRISTOATE (COVALENTLY BOUND) AT 1.96A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA 手法: X-RAY DIFFRACTION / 解像度: 1.96 Å PDB-6geg: TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100); S94A AND MYRISTOATE (COVALENTLY BOUND) AT 2.23A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA 手法: X-RAY DIFFRACTION / 解像度: 2.23 Å PDB-6gei: TEAD4 (216-434);E263A+Y429F COMPLEXED WITH YAP PEPTIDE (60- 100);S94A AND MYRISTOATE (COVALENTLY BOUND TO LYS344, NOT CYS367!) AT 1.65A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-6gek: TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 2.28A (P212121 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA 手法: X-RAY DIFFRACTION / 解像度: 2.28 Å
化合物	ChemComp-MYR: MYRISTIC ACID / ミリスチン酸 ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-HOH: WATER ChemComp-PO4: PHOSPHATE ION / ホスファ-ト
由来	homo sapiens (ヒト)
キーワード	TRANSCRIPTION / transcription factor / co-activator / transcription regulation / PROTEIN-PROTEIN INTERACTION / CO-ACTIVATOR COMPLEX / OTHER