タイトル | Structural Insights into the Substrate Promiscuity of a Laboratory-Evolved Peroxygenase. |
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ジャーナル・号・ページ | Acs Chem. Biol., Vol. 13, Page 3259-3268, Year 2018 |
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掲載日 | 2017年9月7日 (構造データの登録日) |
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著者 | Ramirez-Escudero, M. / Molina-Espeja, P. / Gomez de Santos, P. / Hofrichter, M. / Sanz-Aparicio, J. / Alcalde, M. |
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リンク | Acs Chem. Biol. / PubMed:30376293 |
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手法 | X線回折 |
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解像度 | 1.08 - 1.65 Å |
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構造データ | PDB-5oxt: DIRECT-EVOLUTIONED UNSPECIFIC PEROXYGENASE FROM AGROCYBE AEGERITA, IN COMPLEX WITH ACETATE 手法: X-RAY DIFFRACTION / 解像度: 1.42 Å PDB-5oxu: Direct-evolutioned unspecific peroxygenase from Agrocybe aegerita 手法: X-RAY DIFFRACTION / 解像度: 1.47 Å PDB-5oy1: Direct-evolutioned unspecific peroxygenase from Agrocybe aegerita, in complex with DMSO 手法: X-RAY DIFFRACTION / 解像度: 1.43 Å PDB-5oy2: Direct-evolutioned unspecific peroxygenase from Agrocybe aegerita, in complex with DMP 手法: X-RAY DIFFRACTION / 解像度: 1.36 Å PDB-6ekw: Direct-evolutioned unspecific peroxygenase from Agrocybe aegerita, in complex with naphthalene 手法: X-RAY DIFFRACTION / 解像度: 1.43 Å PDB-6ekx: Direct-evolutioned unspecific peroxygenase from Agrocybe aegerita, in complex with 1-naphthol (I) 手法: X-RAY DIFFRACTION / 解像度: 1.13 Å PDB-6eky: Direct-evolutioned unspecific peroxygenase from Agrocybe aegerita, in complex with 1-naphthol (II) 手法: X-RAY DIFFRACTION / 解像度: 1.23 Å PDB-6ekz: Direct-evolutioned unspecific peroxygenase from Agrocybe aegerita, in complex with propranolol 手法: X-RAY DIFFRACTION / 解像度: 1.08 Å PDB-6el0: Direct-evolutioned unspecific peroxygenase from Agrocybe aegerita, in complex with styrene 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-6el4: Direct-evolutioned unspecific peroxygenase from Agrocybe aegerita, in complex with veratryl alcohol 手法: X-RAY DIFFRACTION / 解像度: 1.53 Å |
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化合物 | |
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由来 | agrocybe aegerita (菌類)
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キーワード | OXIDOREDUCTASE / directed evolution / PaDaI / unspecific peroxygenase / UPO / heme-thiolate peroxidase / Agrocybe aegerita / acetate / DMSO / Dimethylsulfoxide / DMP / 2 / 6-dimethoxyphenol / Naphthalene / 1-naphthol / 1-Naphthalenol / propranolol / styrene / Ethenylbenzene / veratryl alcohol / 3 / 4-Dimethoxybenzyl alcohol |
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