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-Structure paper
タイトル | The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. |
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ジャーナル・号・ページ | Proc. Natl. Acad. Sci. U.S.A., Vol. 115, Page E10022-E10031, Year 2018 |
掲載日 | 2018年6月26日 (構造データの登録日) |
![]() | Knecht, K.M. / Buzovetsky, O. / Schneider, C. / Thomas, D. / Srikanth, V. / Kaderali, L. / Tofoleanu, F. / Reiss, K. / Ferreiros, N. / Geisslinger, G. ...Knecht, K.M. / Buzovetsky, O. / Schneider, C. / Thomas, D. / Srikanth, V. / Kaderali, L. / Tofoleanu, F. / Reiss, K. / Ferreiros, N. / Geisslinger, G. / Batista, V.S. / Ji, X. / Cinatl Jr., J. / Keppler, O.T. / Xiong, Y. |
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手法 | X線回折 |
解像度 | 1.7 - 2.5 Å |
構造データ | ![]() PDB-6dw3: ![]() PDB-6dw4: ![]() PDB-6dw5: ![]() PDB-6dw7: ![]() PDB-6dwd: ![]() PDB-6dwj: ![]() PDB-6dwk: |
化合物 | ![]() ChemComp-HF4: ![]() ChemComp-DTP: ![]() ChemComp-MG: ![]() ChemComp-GTP: ![]() ChemComp-HOH: ![]() ChemComp-HF7: ![]() ChemComp-NA: ![]() ChemComp-GTF: ![]() ChemComp-NI: ![]() ChemComp-GLY: ![]() ChemComp-PO4: ![]() ChemComp-HDV: ![]() ChemComp-SIN: ![]() ChemComp-TCE: ![]() ChemComp-HEJ: ![]() ChemComp-HFD: ![]() ChemComp-TRS: |
由来 |
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![]() | hydrolase/hydrolase inhibitor / Complex / deoxynucleoside triphosphate triphosphohydrolase / dNTPase / nucleotide analogue / cytarabine-TP / HYDROLASE / hydrolase inhibitor / hydrolase-hydrolase inhibitor complex / Cladribine-TP / Gemcitabine-TP / Clofarabine-TP / Vidarabine-TP / Fludarabine-TP |