タイトル | Structural insights into the specificity and catalytic mechanism of mycobacterial nucleotide pool sanitizing enzyme MutT2. |
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ジャーナル・号・ページ | J. Struct. Biol., Vol. 204, Page 449-456, Year 2018 |
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掲載日 | 2018年4月24日 (構造データの登録日) |
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著者 | Singh, A. / Mohammad Arif, S. / Biak Sang, P. / Varshney, U. / Vijayan, M. |
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リンク | J. Struct. Biol. / PubMed:30312643 |
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手法 | X線回折 |
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解像度 | 1.1 - 1.74 Å |
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構造データ | PDB-5zrc: Structural insights into the catalysis mechanism of M. smegmatis antimutator protein MutT2 手法: X-RAY DIFFRACTION / 解像度: 1.1 Å PDB-5zrg: M. smegmatis antimutator protein MutT2 in complex with dCMP 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å PDB-5zrh: M. smegmatis antimutator protein MutT2 in complex with CMP 手法: X-RAY DIFFRACTION / 解像度: 1.54 Å PDB-5zri: M. smegmatis antimutator protein MutT2 in complex with 5m-dCMP 手法: X-RAY DIFFRACTION / 解像度: 1.58 Å PDB-5zrk: M. smegmatis antimutator protein MutT2 in complex with dCTP 手法: X-RAY DIFFRACTION / 解像度: 1.49 Å PDB-5zrl: M. smegmatis antimutator protein MutT2 in complex with CDP 手法: X-RAY DIFFRACTION / 解像度: 1.61 Å PDB-5zro: M. smegmatis antimutator protein MutT2 in complex with 5mdCTP 手法: X-RAY DIFFRACTION / 解像度: 1.41 Å PDB-5zrp: M. smegmatis antimutator protein MutT2 form 3 手法: X-RAY DIFFRACTION / 解像度: 1.74 Å |
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化合物 | ChemComp-9L3: [(2R,3S,5R)-5-(4-azanyl-5-methyl-pyrimidin-1-ium-1-yl)-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate
ChemComp-523: 2'-DEOXY-5-METHYLCYTIDINE 5'-(TETRAHYDROGEN TRIPHOSPHATE)
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由来 | - mycobacterium smegmatis (strain atcc 700084 / mc(2)155) (バクテリア)
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キーワード | HYDROLASE / Nudix hydrolase / MutT / antimutator / CTP pyrophosphorylase / dCMP / CMP / base excision repair / dCTP / CTP / 5mdCTP |
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