タイトル | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex |
---|
ジャーナル・号・ページ | To Be Published |
---|
掲載日 | 2017年10月24日 (構造データの登録日) |
---|
著者 | Wei, S.M. / Yang, L. / Ke, Z.H. / Liu, Q.Y. / Yang, Z.Z. / Chen, Y. / Guo, D.Y. / Fan, C.P. |
---|
リンク | PubMedで検索 |
---|
手法 | X線回折 |
---|
解像度 | 1.68 - 2.27 Å |
---|
構造データ | PDB-5yn5: Crystal structure of MERS-CoV nsp10/nsp16 complex 手法: X-RAY DIFFRACTION / 解像度: 1.96 Å PDB-5yn6: Crystal structure of MERS-CoV nsp10/nsp16 complex bound to SAM 手法: X-RAY DIFFRACTION / 解像度: 1.947 Å PDB-5yn8: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH 手法: X-RAY DIFFRACTION / 解像度: 1.97 Å PDB-5ynb: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to Sinefungin 手法: X-RAY DIFFRACTION / 解像度: 1.98 Å PDB-5ynf: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppA 手法: X-RAY DIFFRACTION / 解像度: 1.791 Å PDB-5yni: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG 手法: X-RAY DIFFRACTION / 解像度: 2.07 Å PDB-5ynj: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppG 手法: X-RAY DIFFRACTION / 解像度: 2.043 Å PDB-5ynm: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppA 手法: X-RAY DIFFRACTION / 解像度: 1.68 Å PDB-5ynn: Crystal structure of MERS-CoV nsp16/nsp10complex bound to sinefungin and m7GpppG 手法: X-RAY DIFFRACTION / 解像度: 1.86 Å PDB-5yno: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH and m7GpppA 手法: X-RAY DIFFRACTION / 解像度: 1.96 Å PDB-5ynp: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to sinefungin and m7GpppA 手法: X-RAY DIFFRACTION / 解像度: 2.27 Å PDB-5ynq: Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH and m7GpppG 手法: X-RAY DIFFRACTION / 解像度: 1.958 Å |
---|
化合物 | |
---|
由来 | human betacoronavirus 2c emc/2012 (ウイルス)
|
---|
キーワード | TRANSFERASE / 2'-O-MTase / complex / inhibitor / cofactor |
---|