EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Optimisation of crystal forms for structure-guided drug discovery
ジャーナル・号・ページ	To be published
掲載日	2020年1月27日 (構造データの登録日)
著者	Brear, P.B. / Fischer, G. / Rocaboy, R. / Marsh, M. / Rossmann, M. / Pantelejevs, T. / Wagstaff, J. / Blaszczyk, B.K.
リンク	PubMedで検索
手法	X線回折
解像度	1.16 - 1.93 Å
構造データ	PDB-5qub: HumRadA1.2 soaked with napht-2,3-diol for 30 seconds at 20 mM 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-5quc: HumRadA1.2 soaked with napht-2,3-diol for 60 seconds at 20 mM 手法: X-RAY DIFFRACTION / 解像度: 1.43 Å PDB-5qud: HumRadA1.2 soaked with napht-2,3-diol for 5 minutes at 20 mM 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å PDB-5que: HumRadA1.2 soaked with napht-2,3-diol for 10 minutes at 20 mM 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å PDB-5quf: HumRadA1.2 soaked with napht-2,3-diol overnight at 20 mM 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-5qug: HumRadA1.2 soaked with napht-2,3-diol overnight at 1 mM 手法: X-RAY DIFFRACTION / 解像度: 1.48 Å PDB-5quh: HumRadA1.2 soaked with napht-2,3-diol overnight at 2 mM 手法: X-RAY DIFFRACTION / 解像度: 1.38 Å PDB-5qui: HumRadA1.2 soaked with napht-2,3-diol overnight at 5 mM 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-5quj: HumRadA1.2 soaked with napht-2,3-diol overnight 10 mM 手法: X-RAY DIFFRACTION / 解像度: 1.42 Å PDB-5quk: Structure of unliganded HumRadA1.2 手法: X-RAY DIFFRACTION / 解像度: 1.16 Å PDB-5qul: Structure of unliganded HumRadA1.3 手法: X-RAY DIFFRACTION / 解像度: 1.278 Å PDB-5qum: Structure of unliganded HumRadA1.4 手法: X-RAY DIFFRACTION / 解像度: 1.93 Å PDB-5qun: Structure of unliganded HumRadA1.6 手法: X-RAY DIFFRACTION / 解像度: 1.24 Å PDB-5quo: HumRadA1 soaked with 0.2 mM indazole in 10% DMSO 手法: X-RAY DIFFRACTION / 解像度: 1.342 Å PDB-5qup: HumRadA1 soaked with 0.5 mM indazole in 10% DMSO 手法: X-RAY DIFFRACTION / 解像度: 1.25 Å PDB-5quq: HumRadA1 soaked with 1 mM indazole in 10% DMSO 手法: X-RAY DIFFRACTION / 解像度: 1.249 Å PDB-5qur: HumRadA1 soaked with 2 mM indazole in 10% DMSO 手法: X-RAY DIFFRACTION / 解像度: 1.247 Å PDB-5qus: HumRadA1 soaked with 5 mM indazole in 10% DMSO 手法: X-RAY DIFFRACTION / 解像度: 1.247 Å PDB-5qut: HumRadA1 soaked with 10 mM indazole in 10% DMSO 手法: X-RAY DIFFRACTION / 解像度: 1.248 Å PDB-5quu: HumRadA1 as soaking control with 10% DMSO 手法: X-RAY DIFFRACTION / 解像度: 1.248 Å
化合物	ChemComp-D48: naphthalene-2,3-diol / 2,3-ジヒドロキシナフタレン ChemComp-PO4: PHOSPHATE ION / ホスファ-ト ChemComp-HOH: WATER ChemComp-LZ1: 1H-indazole / 2H-インダゾ-ル ChemComp-DMS: DIMETHYL SULFOXIDE / 2-チアプロパン2-オキシド / DMSO, 沈殿剤*YM
由来	pyrococcus furiosus (古細菌)
キーワード	DNA BINDING PROTEIN / RAD51 / RadA / inhibition / FBDD / PPI