タイトル | Recognition of protein-linked glycans as a determinant of peptidase activity. |
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ジャーナル・号・ページ | Proc. Natl. Acad. Sci. U.S.A., Vol. 114, Page E679-E688, Year 2017 |
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掲載日 | 2016年6月7日 (構造データの登録日) |
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著者 | Noach, I. / Ficko-Blean, E. / Pluvinage, B. / Stuart, C. / Jenkins, M.L. / Brochu, D. / Buenbrazo, N. / Wakarchuk, W. / Burke, J.E. / Gilbert, M. / Boraston, A.B. |
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リンク | Proc. Natl. Acad. Sci. U.S.A. / PubMed:28096352 |
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手法 | X線回折 |
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解像度 | 1.6 - 2.4 Å |
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構造データ | PDB-5kd2: BT_4244 metallopeptidase from Bacteroides thetaiotaomicron 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-5kd5: BT_4244 metallopeptidase from Bacteroides thetaiotaomicron 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-5kd8: BT_4244 metallopeptidase in complex with Tn antigen. 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-5kdj: ZmpB metallopeptidase from Clostridium perfringens 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-5kdn: ZmpB metallopeptidase from Clostridium perfringens 手法: X-RAY DIFFRACTION / 解像度: 1.66 Å PDB-5kds: ZmpB metallopeptidase in complex with an O-glycopeptide (a2,6-sialylated core-3 pentapeptide). 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-5kdu: ZmpB metallopeptidase in complex with a2,6-Sialyl T-antigen 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-5kdv: IMPa metallopeptidase from Pseudomonas aeruginosa 手法: X-RAY DIFFRACTION / 解像度: 1.93 Å PDB-5kdw: IMPa metallopeptidase from Pseudomonas aeruginosa 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-5kdx: IMPa metallopeptidase in complex with T-antigen 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å |
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化合物 | ChemComp-EPE: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / HEPES / pH緩衝剤*YM
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由来 | bacteroides thetaiotaomicron (バクテリア) bacteroides thetaiotaomicron (strain atcc 29148 / dsm 2079 / nctc 10582 / e50 / vpi-5482) (バクテリア) clostridium perfringens (strain atcc 13124 / dsm 756 / jcm 1290 / ncimb 6125 / nctc 8237 / type a) (ウェルシュ菌)![](img/tx_mammal.gif) bos taurus (ウシ) pseudomonas aeruginosa (strain atcc 15692 / pao1 / 1c / prs 101 / lmg 12228) (緑膿菌)
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キーワード | HYDROLASE / O-Glycopeptidase / PF13402/M60-like / O-glycan / Hydrolase. / Bovine submaxillary mucin / Glycopeptidase / PF13402 / core-1 O-glycan |
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