Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
PDB-5hut: Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å
PDB-5huu: Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate 手法: X-RAY DIFFRACTION / 解像度: 2.37 Å
PDB-5hvl: Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A 手法: X-RAY DIFFRACTION / 解像度: 1.796 Å
PDB-5hvm: Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A 手法: X-RAY DIFFRACTION / 解像度: 2.815 Å
PDB-5hvo: Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A 手法: X-RAY DIFFRACTION / 解像度: 2.467 Å