EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
ジャーナル・号・ページ	Nat. Chem. Biol., Vol. 12, Page 741-747, Year 2016
掲載日	2015年10月22日 (構造データの登録日)
著者	Hai, Y. / Christianson, D.W.
リンク	Nat. Chem. Biol. / PubMed:27454933
手法	X線回折
解像度	1.32 - 2.79 Å
構造データ	PDB-5edu: Crystal structure of human histone deacetylase 6 catalytic domain 2 in complex with trichostatin A 手法: X-RAY DIFFRACTION / 解像度: 2.79 Å PDB-5eef: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 in complex with trichostatin A 手法: X-RAY DIFFRACTION / 解像度: 2.151 Å PDB-5eei: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with SAHA 手法: X-RAY DIFFRACTION / 解像度: 1.32 Å PDB-5eek: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with trichostatin A 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å PDB-5eem: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-5een: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with belinostat 手法: X-RAY DIFFRACTION / 解像度: 1.861 Å PDB-5ef7: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HPOB 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-5ef8: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with panobinostat 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-5efb: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with oxamflatin 手法: X-RAY DIFFRACTION / 解像度: 2.543 Å PDB-5efg: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with acetate 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-5efh: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with trifluoroketone transition state analogue 手法: X-RAY DIFFRACTION / 解像度: 2.162 Å PDB-5efj: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HC toxin 手法: X-RAY DIFFRACTION / 解像度: 1.73 Å PDB-5efk: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (Y745F mutant) in complex with alpha tubulin K40 tripeptide substrate 手法: X-RAY DIFFRACTION / 解像度: 1.82 Å PDB-5efn: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (H574A) in complex with histone H4 Lys6 tripeptide substrate 手法: X-RAY DIFFRACTION / 解像度: 1.804 Å
化合物	ChemComp-TSN: TRICHOSTATIN A ChemComp-ZN: Unknown entry ChemComp-K: Unknown entry ChemComp-HOH: WATER ChemComp-NH4: AMMONIUM ION ChemComp-SO4: SULFATE ION ChemComp-EDO: 1,2-ETHANEDIOL ChemComp-SHH: OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE ChemComp-GOL: GLYCEROL ChemComp-CL: Unknown entry ChemComp-MG: Unknown entry ChemComp-IOD: IODIDE ION ChemComp-NA: Unknown entry ChemComp-FMT: FORMIC ACID ChemComp-5OG: Belinostat / 阻害剤YM ChemComp-5OJ: 4-[2-[2-hydroxyethyl(phenyl)amino]-2-oxidanylidene-ethyl]-~{N}-oxidanyl-benzamide ChemComp-LBH: Panobinostat / 薬剤, 阻害剤YM ChemComp-5OK: Oxamflatin ChemComp-ACT: ACETATE ION ChemComp-FKS: 7-[(3-aminopropyl)amino]-1,1,1-trifluoroheptane-2,2-diol ChemComp-BR: BROMIDE ION ChemComp-NO3: NITRATE ION ChemComp-PEG: DI(HYDROXYETHYL)ETHER ChemComp-MCM: 7-AMINO-4-METHYL-CHROMEN-2-ONE
由来	escherichia coli (大腸菌) homo sapiens (ヒト) danio rerio (ゼブラフィッシュ) bipolaris zeicola (菌類)
キーワード	HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR complex / HYDROLASE