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-Structure paper
タイトル | Crystal Structures of Human Rip2 Kinase Catalytic Domain Complexed with ATP-Competitive Inhibitors: Foundations for Understanding Inhibitor Selectivity. |
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ジャーナル・号・ページ | Bioorg. Med. Chem., Vol. 23, Page 7000-, Year 2015 |
掲載日 | 2015年9月23日 (構造データの登録日) |
![]() | Charnley, A.K. / Convery, M.A. / Lakdawala Shah, A. / Jones, E. / Hardwicke, P. / Bridges, A. / Ouellette, M. / Totoritis, R. / Schwartz, B. / King, B.W. ...Charnley, A.K. / Convery, M.A. / Lakdawala Shah, A. / Jones, E. / Hardwicke, P. / Bridges, A. / Ouellette, M. / Totoritis, R. / Schwartz, B. / King, B.W. / Wisnoski, D.D. / Kang, J. / Eidam, P.M. / Votta, B.J. / Gough, P.J. / Marquis, R.W. / Bertin, J. / Casillas, L. |
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手法 | X線回折 |
解像度 | 2.44 - 3.23 Å |
構造データ | ![]() PDB-5ar2: ![]() PDB-5ar3: ![]() PDB-5ar4: ![]() PDB-5ar5: ![]() PDB-5ar7: ![]() PDB-5ar8: |
化合物 | ![]() ChemComp-CA: ![]() ChemComp-HOH: ![]() ChemComp-ACP: ![]() ChemComp-MG: ![]() ChemComp-SB2: ![]() ChemComp-IQ7: ![]() ChemComp-SR8: ![]() ChemComp-XYW: |
由来 |
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![]() | TRANSFERASE / KINASE DOMAIN / KINASE INHIBITOR / STRUCTURE-BASED DRUG DESIGN / INHIBITOR SELECTIVITY |