EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases
ジャーナル・号・ページ	Chemmedchem, Vol. 10, Page 662-687, Year 2015
掲載日	2014年6月3日 (構造データの登録日)
著者	Dudutiene, V. / Zubriene, A. / Smirnov, A. / Timm, D.D. / Smirnoviene, J. / Kazokaite, J. / Michailoviene, V. / Zaksauskas, A. / Manakova, E. / Grazulis, S. / Matulis, D.
リンク	Chemmedchem / PubMed:25758852
手法	X線回折
解像度	1.3 - 1.95 Å
構造データ	PDB-4qiy: Crystal structure of human carbonic anhydrase isozyme II with inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å PDB-4qiz: Crystal structure of human carbonic anhydrase isozyme XIII with inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-4qj0: Crystal structure of catalytic domain of human carbonic anhydrase isozyme XII with inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-4qjm: Crystal structure of human carbonic anhydrase isozyme II with inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-4qjo: Crystal structure of catalytic domain of human carbonic anhydrase isozyme XII with inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-4qjp: Crystal structure of human carbonic anhydrase isozyme XIII with inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-4qjw: Crystal structure of catalytic domain of human carbonic anhydrase isozyme XII with inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-4qjx: Crystal structure of human carbonic anhydrase isozyme XIII with inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-4qtl: Crystal structure of human carbonic anhydrase isozyme II with inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-WWX: 2,3,6-trifluoro-5-{[(1R,2S)-2-hydroxy-1,2-diphenylethyl]amino}-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide ChemComp-DMS: DIMETHYL SULFOXIDE / 2-チアプロパン2-オキシド / DMSO, 沈殿剤YM ChemComp-BCN: BICINE / N,N-ビス(2-ヒドロキシエチル)グリシン / pH緩衝剤YM ChemComp-HOH: WATER ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-V1F: 3-(benzylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide ChemComp-MES: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID / 2-モルホリノエタンスルホン酸 / pH緩衝剤YM ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル ChemComp-CIT: CITRIC ACID / クエン酸 ChemComp-WWO*: 3-(benzylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
由来	homo sapiens (ヒト)
キーワード	LYASE/LYASE INHIBITOR / drug design / carbonic anhydrase / benzenesulfonamide / metal-binding / LYASE-LYASE INHIBITOR complex