EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo.
ジャーナル・号・ページ	J. Virol., Vol. 88, Page 12669-12682, Year 2014
掲載日	2014年1月25日 (構造データの登録日)
著者	Rudicell, R.S. / Kwon, Y.D. / Ko, S.Y. / Pegu, A. / Louder, M.K. / Georgiev, I.S. / Wu, X. / Zhu, J. / Boyington, J.C. / Chen, X. ...Rudicell, R.S. / Kwon, Y.D. / Ko, S.Y. / Pegu, A. / Louder, M.K. / Georgiev, I.S. / Wu, X. / Zhu, J. / Boyington, J.C. / Chen, X. / Shi, W. / Yang, Z.Y. / Doria-Rose, N.A. / McKee, K. / O'Dell, S. / Schmidt, S.D. / Chuang, G.Y. / Druz, A. / Soto, C. / Yang, Y. / Zhang, B. / Zhou, T. / Todd, J.P. / Lloyd, K.E. / Eudailey, J. / Roberts, K.E. / Donald, B.R. / Bailer, R.T. / Ledgerwood, J. / Mullikin, J.C. / Shapiro, L. / Koup, R.A. / Graham, B.S. / Nason, M.C. / Connors, M. / Haynes, B.F. / Rao, S.S. / Roederer, M. / Kwong, P.D. / Mascola, J.R. / Nabel, G.J.
リンク	J. Virol. / PubMed:25142607
手法	X線回折
解像度	2.1 - 2.709 Å
構造データ	PDB-4olu: Crystal structure of antibody VRC07 in complex with clade A/E 93TH057 HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 2.202 Å PDB-4olv: Crystal structure of antibody VRC07-G54F in complex with clade A/E 93TH057 HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-4olw: Crystal structure of antibody VRC07-G54H in complex with clade A/E 93TH057 HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 2.709 Å PDB-4olx: Crystal structure of antibody VRC07-G54L in complex with clade A/E 93TH057 HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-4oly: Crystal structure of antibody VRC07-G54R in complex with clade A/E 93TH057 HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 2.351 Å PDB-4olz: Crystal structure of antibody VRC07-G54W in complex with clade A/E 93TH057 HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-4om0: Crystal structure of antibody VRC07-G54Y in complex with clade A/E 93TH057 HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 2.289 Å PDB-4om1: Crystal structure of antibody VRC07-I30Q, G54W, S58N in complex with clade A/E 93TH057 HIV-1 gp120 core 手法: X-RAY DIFFRACTION / 解像度: 2.131 Å
化合物	ChemComp-NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose / N-アセチル-β-D-グルコサミン ChemComp-HOH: WATER
由来	human immunodeficiency virus 1 (ヒト免疫不全ウイルス) homo sapiens (ヒト)
キーワード	VIRAL PROTEIN/IMMUNE SYSTEM / VRC07 antibody / Passive transfer / Neutralization / In vivo protection / Autoreactivity / Lentiviral infection / Enhanced potency / HIV-1 gp120 / VIRAL PROTEIN-IMMUNE SYSTEM complex / VRC07-G54F / VRC07-G54H / VRC07-G54L / VRC07-G54R / VRC07-G54W / VRC07-G54Y / VRC07-I30Q