EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
ジャーナル・号・ページ	J. Med. Chem., Vol. 56, Page 8497-8511, Year 2013
掲載日	2013年3月14日 (構造データの登録日)
著者	Rouhana, J. / Hoh, F. / Estaran, S. / Henriquet, C. / Boublik, Y. / Kerkour, A. / Trouillard, R. / Martinez, J. / Pugniere, M. / Padilla, A. / Chavanieu, A.
リンク	J. Med. Chem. / PubMed:24112024
手法	X線回折
解像度	1.47 - 1.95 Å
構造データ	PDB-4jmi: Sec7 domain of ARNO, an exchange factor, at 1.5 Angstrom resolution 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-4jmo: Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-4jwl: Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH7.5 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-4jxh: Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH 8.5 手法: X-RAY DIFFRACTION / 解像度: 1.47 Å PDB-4l5m: Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH6.5 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å
化合物	ChemComp-HOH: WATER ChemComp-JAF: N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide ChemComp-HRC: N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide ChemComp-PO4: PHOSPHATE ION / ホスファ-ト
由来	homo sapiens (ヒト)
キーワード	SIGNALING PROTEIN / Nucleotide Exchange Factors / Arf1 / SIGNALING PROTEIN/INHIBITOR / Nucleotide exchange factor / SIGNALING PROTEIN-INHIBITOR complex / sec 7 domain / sec-7domain