EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human Cad.
ジャーナル・号・ページ	Structure, Vol. 22, Page 185-, Year 2014
掲載日	2013年7月17日 (構造データの登録日)
著者	Grande-Garcia, A. / Lallous, N. / Diaz-Tejada, C. / Ramon-Maiques, S.
リンク	Structure / PubMed:24332717
手法	X線回折
解像度	1.261 - 1.899 Å
構造データ	PDB-4by3: Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from E. coli. 手法: X-RAY DIFFRACTION / 解像度: 1.73 Å PDB-4c6b: Crystal structure of the dihydroorotase domain of human CAD with incomplete active site, obtained recombinantly from E. coli. 手法: X-RAY DIFFRACTION / 解像度: 1.656 Å PDB-4c6c: Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from HEK293 cells. 手法: X-RAY DIFFRACTION / 解像度: 1.451 Å PDB-4c6d: Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 6.0 手法: X-RAY DIFFRACTION / 解像度: 1.298 Å PDB-4c6e: Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 5.5 手法: X-RAY DIFFRACTION / 解像度: 1.263 Å PDB-4c6f: Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 6.5 手法: X-RAY DIFFRACTION / 解像度: 1.261 Å PDB-4c6i: Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 7.0 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-4c6j: Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 7.5 手法: X-RAY DIFFRACTION / 解像度: 1.299 Å PDB-4c6k: Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 8.0 手法: X-RAY DIFFRACTION / 解像度: 1.478 Å PDB-4c6l: Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 6.0 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-4c6m: Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 7.0 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-4c6n: Crystal structure of the dihydroorotase domain of human CAD E1637T mutant bound to substrate at pH 6.0 手法: X-RAY DIFFRACTION / 解像度: 1.899 Å PDB-4c6o: Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 6.0 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-4c6p: Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 7.0 手法: X-RAY DIFFRACTION / 解像度: 1.518 Å PDB-4c6q: Crystal structure of the dihydroorotase domain of human CAD C1613S mutant bound to substrate at pH 7.0 手法: X-RAY DIFFRACTION / 解像度: 1.659 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-FMT: FORMIC ACID / ギ酸 ChemComp-HOH: WATER ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-DOR: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID / ジヒドロオロト酸 ChemComp-NCD: N-CARBAMOYL-L-ASPARTATE / N-カルバモイル-L-アスパラギン酸 ChemComp-FOT: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID / 5-フルオロオロト酸 ChemComp-ORO: OROTIC ACID / オロチン酸
由来	homo sapiens (ヒト)
キーワード	HYDROLASE / DE NOVO PYRIMIDINE BIOSYNTHESIS / AMIDOHYDROLASE SUPERFAMILY / METALLOENZYME / ZINC BINDING / HISTIDINATE ANION