タイトル | Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases. |
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ジャーナル・号・ページ | Biochemistry, Vol. 51, Page 7043-, Year 2012 |
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掲載日 | 2012年8月9日 (構造データの登録日) |
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著者 | Franceschini, S. / Fedkenheuer, M. / Vogelaar, N.J. / Robinson, H.H. / Sobrado, P. / Mattevi, A. |
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リンク | Biochemistry / PubMed:22928747 |
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手法 | X線回折 |
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解像度 | 1.9 - 2.9 Å |
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構造データ | PDB-4b63: A. fumigatus ornithine hydroxylase (SidA) bound to NADP and ornithine 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-4b64: A. fumigatus ornithine hydroxylase (SidA) bound to NADP and Lysine 手法: X-RAY DIFFRACTION / 解像度: 2.28 Å PDB-4b65: A. fumigatus ornithine hydroxylase (SidA), reduced state bound to NADP(H) 手法: X-RAY DIFFRACTION / 解像度: 2.32 Å PDB-4b66: A. fumigatus ornithine hydroxylase (SidA), reduced state bound to NADP and Arg 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-4b67: A. fumigatus ornithine hydroxylase (SidA), re-oxidised state bound to NADP and ornithine 手法: X-RAY DIFFRACTION / 解像度: 2.75 Å PDB-4b68: A. fumigatus ornithine hydroxylase (SidA), re-oxidised state bound to NADP and Arg 手法: X-RAY DIFFRACTION / 解像度: 2.29 Å PDB-4b69: A. fumigatus ornithine hydroxylase (SidA) bound to ornithine 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å |
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化合物 | ChemComp-NAP: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
ChemComp-NDP: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE / NADPH
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由来 | ![](img/tx_fungus.gif) aspergillus fumigatus (カビ)
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キーワード | OXIDOREDUCTASE / SIDEROPHORE / FLAVIN |
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