EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa.
ジャーナル・号・ページ	ACS Chem. Biol., Vol. 8, Page 387-396, Year 2013
掲載日	2013年2月1日 (構造データの登録日)
著者	Alphey, M.S. / Pirrie, L. / Torrie, L.S. / Boulkeroua, W.A. / Gardiner, M. / Sarkar, A. / Maringer, M. / Oehlmann, W. / Brenk, R. / Scherman, M.S. ...Alphey, M.S. / Pirrie, L. / Torrie, L.S. / Boulkeroua, W.A. / Gardiner, M. / Sarkar, A. / Maringer, M. / Oehlmann, W. / Brenk, R. / Scherman, M.S. / McNeil, M. / Rejzek, M. / Field, R.A. / Singh, M. / Gray, D. / Westwood, N.J. / Naismith, J.H.
リンク	ACS Chem. Biol. / PubMed:23138692
手法	X線回折
解像度	1.7 - 2.505 Å
構造データ	PDB-3zlk: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.952 Å PDB-3zll: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-4arw: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.204 Å PDB-4asj: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-4asy: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-4b2w: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.36 Å PDB-4b2x: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-4b3u: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-4b42: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.505 Å PDB-4b4b: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-4b4g: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-4b4m: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.35 Å PDB-4b5b: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.055 Å
化合物	ChemComp-Y46: N-(6-AMINO-1-BENZYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)BENZENESULFONAMIDE ChemComp-CL: Unknown entry ChemComp-HOH: WATER ChemComp-4WF: 5-azanyl-6-oxidanyl-1-(phenylmethyl)pyrimidine-2,4-dione ChemComp-MES: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH緩衝剤YM ChemComp-GOL: GLYCEROL ChemComp-HNR: N-(6-AMINO-1-BUTYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL)-N-METHYL-BENZENESULFONAMIDE ChemComp-N6A: N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-methylbenzenesulfonamide ChemComp-PO4: PHOSPHATE ION ChemComp-N5Y: N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-methylbenzamide ChemComp-BZ0: N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)benzamide ChemComp-NIQ: 6-amino-1-butyl-5-(cyclopentylamino)pyrimidine-2,4(1H,3H)-dione ChemComp-NWL: 6-amino-1-benzyl-5-(ethylamino)pyrimidine-2,4(1H,3H)-dione ChemComp-942: N-[6-azanyl-1-butyl-2,4-bis(oxidanylidene)pyrimidin-5-yl]-N-methyl-benzamide ChemComp-GJB: 1-(2-phenylethyl)pyrimidine-2,4,6(1H,3H,5H)-trione ChemComp-KKT: N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-methylbutane-1-sulfonamide ChemComp-JWT: N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-fluoro-N-methylbenzenesulfonamide ChemComp-BBE*: N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N,3-dimethylbenzenesulfonamide
由来	pseudomonas aeruginosa pao1 (緑膿菌) pseudomonas aeruginosa (緑膿菌)
キーワード	TRANSFERASE / THYMIDYLYLTRANSFERASE / ALLOSTERIC INHIBITOR