EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography.
ジャーナル・号・ページ	Bioorg. Med. Chem., Vol. 22, Page 2427-2434, Year 2014
掲載日	2013年10月17日 (構造データの登録日)
著者	Amano, Y. / Yamaguchi, T. / Tanabe, E.
リンク	Bioorg. Med. Chem. / PubMed:24656800
手法	X線回折
解像度	2.01 - 2.77 Å
構造データ	PDB-3wk4: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.11 Å PDB-3wk5: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.77 Å PDB-3wk6: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-3wk7: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-3wk8: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-3wk9: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-3wka: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.01 Å PDB-3wkb: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-3wkc: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-3wkd: Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 手法: X-RAY DIFFRACTION / 解像度: 2.48 Å PDB-3wke: Crystal structure of soluble epoxide hydrolase in complex with t-AUCB 手法: X-RAY DIFFRACTION / 解像度: 2.75 Å
化合物	ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-PO4: PHOSPHATE ION / ホスファ-ト ChemComp-S0A: 1-[(1R)-1-cyclopropylethyl]-3-phenylurea ChemComp-HOH: WATER ChemComp-S0C: 2-cyclopentyl-N-(1,3-thiazol-2-yl)acetamide ChemComp-S0B: (5R)-5-methyl-N-(2-phenylethyl)-4,5-dihydro-1,3-thiazol-2-amine ChemComp-S0D: 2-(1-methyl-1H-pyrazol-4-yl)-1H-benzimidazole ChemComp-S0E: 6-(trifluoromethyl)-1,3-benzothiazol-2-amine / 6-トリフルオロメチルベンゾチアゾ-ル-2-アミン ChemComp-S0F: 5-(4-bromobenzyl)-1,3-thiazol-2-amine ChemComp-S0G: 6-amino-1-methyl-5-(piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione ChemComp-S0I: 4-benzyl-3,4-dihydroquinoxalin-2(1H)-one ChemComp-S0J: 4-{2,5-dimethyl-1-[(2R)-tetrahydrofuran-2-ylmethyl]-1H-pyrrol-3-yl}-1,3-thiazol-2-amine ChemComp-S0K: N-[2-(morpholin-4-yl)phenyl]thiophene-3-carboxamide ChemComp-AUB: 4-[(trans-4-{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]dec-1-ylcarbamoyl]amino}cyclohexyl)oxy]benzoic acid / 1-(アダマンタン-1-イル)-3-[4β-(4-カルボキシフェノキシ)シクロヘキサン-1α-イル]尿素
由来	homo sapiens (ヒト)
キーワード	HYDROLASE/HYDROLASE INHIBITOR / Hydrolase / HYDROLASE-HYDROLASE INHIBITOR complex