EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase.
ジャーナル・号・ページ	Acta Crystallogr. ,Sect. D, Vol. 66, Page 1271-1277, Year 2010
掲載日	2010年7月14日 (構造データの登録日)
著者	Cody, V. / Piraino, J. / Pace, J. / Li, W. / Gangjee, A.
リンク	Acta Crystallogr. ,Sect. D / PubMed:21123866
手法	X線回折
解像度	1.35 - 1.9 Å
構造データ	PDB-3nxo: Perferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-3nxr: Perferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-3nxt: Preferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E-and Z-isomers of a Series of 5-substituted 2,4-diaminofuro[2m,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-3nxv: Preferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-3nxx: Preferential Selection of Isomer Binding from Chiral Mixtures: Alternate Binding Modes Observed for the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro-2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-3nxy: Preferential Selection of Isomer Binding from Chiral Mixtures: Alernate Binding Modes Observed fro the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å
化合物	ChemComp-D2B: 5-[(1Z)-2-(2-methoxyphenyl)-3-methylbut-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-NDP: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE / NADPH ChemComp-HOH: WATER ChemComp-D2D: 5-[(1E)-2-(2-methoxyphenyl)-4-methylpent-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine ChemComp-D2E: 5-[(E)-2-cyclopropyl-2-(2-methoxyphenyl)ethenyl]furo[2,3-d]pyrimidine-2,4-diamine ChemComp-D2F: 5-[(1E)-2-(2-methoxyphenyl)hex-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine ChemComp-D2H: 5-[(1E,3R)-2-(2-methoxyphenyl)-3-methylpent-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine
由来	homo sapiens (ヒト)
キーワード	OXIDOREDUCTASE / E-Z-isomers binding preferences / chiral selection E- Z-isomers / chiral selectivity E-Z-isomers / chiral mixture / E-Z-isomers / chiral mixtures preferential selection / chiral mixtures preferential binding