EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
ジャーナル・号・ページ	Biochemistry, Vol. 49, Page 443-451, Year 2010
掲載日	2009年12月21日 (構造データの登録日)
著者	Sim, L. / Jayakanthan, K. / Mohan, S. / Nasi, R. / Johnston, B.D. / Pinto, B.M. / Rose, D.R.
リンク	Biochemistry / PubMed:20039683
手法	X線回折
解像度	1.8 - 2.1 Å
構造データ	PDB-3l4t: Crystal complex of N-terminal Human Maltase-Glucoamylase with BJ2661 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-3l4u: Crystal complex of N-terminal Human Maltase-Glucoamylase with de-O-sulfonated kotalanol 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-3l4v: Crystal complex of N-terminal Human Maltase-Glucoamylase with kotalanol 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-3l4w: Crystal complex of N-terminal Human Maltase-Glucoamylase with miglitol 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å PDB-3l4x: Crystal complex of N-terminal Human Maltase-Glucoamylase with NR4-8 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-3l4y: Crystal complex of N-terminal Human Maltase-Glucoamylase with NR4-8II 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-3l4z: Crystal complex of N-terminal Human Maltase-Glucoamylase with Salacinol 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å
化合物	ChemComp-BJ1: (1R,2S)-1-[(1S)-1,2-dihydroxyethyl]-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-2-hydroxypropyl sulfate ChemComp-NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose / N-アセチル-β-D-グルコサミン / N-アセチルグルコサミン ChemComp-HOH: WATER / 水 ChemComp-DSK: (2R,3S,4S)-1-[(2S,3S,4R,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl]-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium (non-preferred name) ChemComp-SO4: SULFATE ION / 硫酸ジアニオン / 硫酸塩 ChemComp-KTL: (1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate ChemComp-MIG: (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol / ミグリト-ル / ミグリトール ChemComp-GOL: GLYCEROL / グリセロ-ル / グリセリン ChemComp-NR3: (1S,2R,3S,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate ChemComp-NR4: (1S,2R,3S,4R)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate ChemComp-SSD: 1,4-DIDEOXY-1,4-[[2R,3R)-2,4-DIHYDROXY-3-(SULFOXY)BUTYL]EPISULFONIUMYLIDENE]-D-ARABINITOL INNER SALT
由来	homo sapiens (ヒト)
キーワード	HYDROLASE (加水分解酵素) / Glycoside Hydrolase Family 31 / Cell membrane (細胞膜) / Disulfide bond (ジスルフィド) / Glycoprotein (糖タンパク質) / Glycosidase / Membrane (生体膜) / Multifunctional enzyme / Polymorphism / Signal-anchor / Sulfation / Transmembrane (膜貫通型タンパク質)