タイトル | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae |
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ジャーナル・号・ページ | To be Published |
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掲載日 | 2009年10月31日 (構造データの登録日) |
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著者 | Jorgensen, R. / Edwards, P.R. / Merrill, A.R. |
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リンク | PubMedで検索 |
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手法 | X線回折 |
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解像度 | 1.27 - 1.65 Å |
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構造データ | PDB-3ki0: Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-D 手法: X-RAY DIFFRACTION / 解像度: 1.29 Å PDB-3ki1: Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-F 手法: X-RAY DIFFRACTION / 解像度: 1.43 Å PDB-3ki2: Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-G 手法: X-RAY DIFFRACTION / 解像度: 1.28 Å PDB-3ki3: Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-H 手法: X-RAY DIFFRACTION / 解像度: 1.27 Å PDB-3ki4: Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-P 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-3ki5: Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-M 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-3ki6: Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-L 手法: X-RAY DIFFRACTION / 解像度: 1.54 Å PDB-3ki7: Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-I 手法: X-RAY DIFFRACTION / 解像度: 1.32 Å |
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化合物 | ChemComp-G9D: 3-(morpholin-4-ylmethyl)-1,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one / GP-D
ChemComp-G9P: (11bR)-3-oxo-1,2,3,11b-tetrahydrochromeno[4,3,2-de]isoquinoline-10-sulfonic acid
ChemComp-G9L: 8-fluoro-2-(3-piperidin-1-ylpropanoyl)-1,3,4,5-tetrahydrobenzo[c][1,6]naphthyridin-6(2H)-one / 2-(3-ピペリジノプロピオニル)-8-フルオロ-1,2,3,4,5,6-ヘキサヒドロベンゾ[c][1,6]ナフチリジ(以下略)
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由来 | ![](img/tx_bacteria.gif) vibrio cholerae (コレラ菌)
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キーワード | Transferase / toxin / ADP-ribosyl transferase / alpha-beta complex / diphthamide |
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