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-Structure paper
タイトル | Thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV: structure-based drug design, synthesis, and biological evaluation. |
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ジャーナル・号・ページ | Bioorg. Med. Chem., Vol. 18, Page 3307-3319, Year 2010 |
掲載日 | 2008年11月7日 (構造データの登録日) |
![]() | Vernier, W. / Chong, W. / Rewolinski, D. / Greasley, S. / Pauly, T. / Shaw, M. / Dinh, D. / Ferre, R.A. / Nukui, S. / Ornelas, M. / Reyner, E. |
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手法 | X線回折 |
解像度 | 1.72 - 2.05 Å |
構造データ | ![]() PDB-3f7b: ![]() PDB-3f7u: ![]() PDB-3fw3: |
化合物 | ![]() ChemComp-ZN: ![]() ChemComp-AG5: ![]() ChemComp-HOH: ![]() ChemComp-AG4: ![]() ChemComp-ETS: ![]() ChemComp-GLC: ![]() ChemComp-SO4: |
由来 |
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![]() | LYASE / Structure-based drug design. Small molecule complex. CO-CRYSTAL. / Cell membrane / Disease mutation / Glycoprotein / GPI-anchor / Lipoprotein / Membrane / Metal-binding / Retinitis pigmentosa / Sensory transduction / Vision / Zinc / STRUCTURE-BASED DRUG DESIGN. SMALL MOLECULE COMPLEX. CO-CRYSTAL / Polymorphism |