EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
ジャーナル・号・ページ	Biochemistry, Vol. 48, Page 1322-1331, Year 2009
掲載日	2008年5月26日 (構造データの登録日)
著者	Genis, C. / Sippel, K.H. / Case, N. / Cao, W. / Avvaru, B.S. / Tartaglia, L.J. / Govindasamy, L. / Tu, C. / Agbandje-McKenna, M. / Silverman, D.N. ...Genis, C. / Sippel, K.H. / Case, N. / Cao, W. / Avvaru, B.S. / Tartaglia, L.J. / Govindasamy, L. / Tu, C. / Agbandje-McKenna, M. / Silverman, D.N. / Rosser, C.J. / McKenna, R.
リンク	Biochemistry / PubMed:19170619
手法	X線回折
解像度	1.48 - 1.8 Å
構造データ	PDB-3d8w: Use of a carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-3d9z: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-3daz: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-3dbu: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-3dc3: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-3dc9: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-3dcc: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-3dcs: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-3dcw: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-3dd0: Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 手法: X-RAY DIFFRACTION / 解像度: 1.48 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-D8W: 5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide ChemComp-HOH: WATER ChemComp-D9Z: 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide ChemComp-MZM: N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide / 阻害剤YM ChemComp-AZM: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE / 薬剤YM ChemComp-EZL: 6-ethoxy-1,3-benzothiazole-2-sulfonamide / 薬剤, 阻害剤*YM
由来	homo sapiens (ヒト)
キーワード	LYASE / carbonic Anhydrase II / Anti-Cancer / benzolamide / Acetylation / Cytoplasm / Disease mutation / Metal-binding / Polymorphism / Zinc / Carbonic anhydrase II complex / CAIX mimic inhibitors