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-Structure paper
タイトル | Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs). |
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ジャーナル・号・ページ | Bioorg. Med. Chem. Lett., Vol. 18, Page 554-559, Year 2008 |
掲載日 | 2007年9月27日 (構造データの登録日) |
![]() | Zhao, Z. / Wolkenberg, S.E. / Lu, M. / Munshi, V. / Moyer, G. / Feng, M. / Carella, A.V. / Ecto, L.T. / Gabryelski, L.J. / Lai, M.T. ...Zhao, Z. / Wolkenberg, S.E. / Lu, M. / Munshi, V. / Moyer, G. / Feng, M. / Carella, A.V. / Ecto, L.T. / Gabryelski, L.J. / Lai, M.T. / Prasad, S.G. / Yan, Y. / McGaughey, G.B. / Miller, M.D. / Lindsley, C.W. / Hartman, G.D. / Vacca, J.P. / Williams, T.M. |
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手法 | X線回折 |
解像度 | 2.4 Å |
構造データ | ![]() PDB-2rf2: |
化合物 | ![]() ChemComp-MRX: ![]() ChemComp-HOH: |
由来 |
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![]() | TRANSFERASE / HIV-1 revers transcriptase / AIS / non-nucleoside inhibition / nucleotidyltransferase / AIDS / Aspartyl protease / Capsid maturation / Core protein / Cytoplasm / DNA integration / DNA recombination / DNA-directed DNA polymerase / Endonuclease / Host-virus interaction / Hydrolase / Lipoprotein / Magnesium / Membrane / Metal-binding / Multifunctional enzyme / Myristate / Nuclease / Nucleus / Phosphorylation / Protease / RNA-binding / RNA-directed DNA polymerase / Viral nucleoprotein / Virion / Zinc / Zinc-finger |