タイトル | Structural definition of a conserved neutralization epitope on HIV-1 gp120. |
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ジャーナル・号・ページ | Nature, Vol. 445, Page 732-737, Year 2007 |
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掲載日 | 2006年11月20日 (構造データの登録日) |
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著者 | Zhou, T. / Xu, L. / Dey, B. / Hessell, A.J. / Van Ryk, D. / Xiang, S.H. / Yang, X. / Zhang, M.Y. / Zwick, M.B. / Arthos, J. ...Zhou, T. / Xu, L. / Dey, B. / Hessell, A.J. / Van Ryk, D. / Xiang, S.H. / Yang, X. / Zhang, M.Y. / Zwick, M.B. / Arthos, J. / Burton, D.R. / Dimitrov, D.S. / Sodroski, J. / Wyatt, R. / Nabel, G.J. / Kwong, P.D. |
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リンク | Nature / PubMed:17301785 |
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手法 | X線回折 |
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解像度 | 1.99 - 2.8 Å |
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構造データ | PDB-2nxy: HIV-1 gp120 Envelope Glycoprotein(S334A) Complexed with CD4 and Antibody 17b 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-2nxz: HIV-1 gp120 Envelope Glycoprotein (T257S, S334A, S375W) Complexed with CD4 and Antibody 17b 手法: X-RAY DIFFRACTION / 解像度: 2.04 Å PDB-2ny0: HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, T257S, V275C, S334A, S375W, A433M) Complexed with CD4 and Antibody 17b 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-2ny1: HIV-1 gp120 Envelope Glycoprotein (I109C, T257S, S334A, S375W, Q428C) Complexed with CD4 and Antibody 17b 手法: X-RAY DIFFRACTION / 解像度: 1.99 Å PDB-2ny2: HIV-1 gp120 Envelope Glycoprotein (T123C, T257S, S334A, S375W, G431C) Complexed with CD4 and Antibody 17b 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-2ny3: HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E267C, S334A, S375W) Complexed with CD4 and Antibody 17b 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-2ny4: HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E268C, S334A, S375W) Complexed with CD4 and Antibody 17b 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-2ny5: HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T257S, V275C, S334A, S375W, Q428C, A433M) Complexed with CD4 and Antibody 17b 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-2ny6: HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T123C, T257S, V275C,S334A, S375W, Q428C, G431C) Complexed with CD4 and Antibody 17b 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-2ny7: HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å |
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化合物 | |
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由来 | - human immunodeficiency virus 1 (ヒト免疫不全ウイルス)
- homo sapiens (ヒト)
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キーワード | VIRAL PROTEIN/IMMUNE SYSTEM / HIV / gp120 / antibody / CD4 / VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX / broadly neutralizing antibody / b12 |
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