タイトル | Cold denaturation of a protein dimer monitored at atomic resolution. |
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ジャーナル・号・ページ | Nat. Chem. Biol., Vol. 9, Page 264-270, Year 2013 |
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掲載日 | 2012年9月19日 (構造データの登録日) |
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著者 | Jaremko, M. / Jaremko, L. / Kim, H.Y. / Cho, M.K. / Schwieters, C.D. / Giller, K. / Becker, S. / Zweckstetter, M. |
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リンク | Nat. Chem. Biol. / PubMed:23396077 |
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手法 | NMR (溶液) |
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構造データ | PDB-2lyj: NOE-based 3D structure of the CylR2 homodimer at 298K 手法: SOLUTION NMR PDB-2lyk: NOE-based 3D structure of the CylR2 homodimer at 270K (-3 Celsius degrees) 手法: SOLUTION NMR PDB-2lyl: NOE-based 3D structure of the predissociated homodimer of CylR2 in equilibrium with monomer at 266K (-7 Celsius degrees) 手法: SOLUTION NMR PDB-2lyp: NOE-based 3D structure of the monomer of CylR2 in equilibrium with predissociated homodimer at 266K (-7 Celsius degrees) 手法: SOLUTION NMR PDB-2lyq: NOE-based 3D structure of the monomeric intermediate of CylR2 at 262K (-11 Celsius degrees) 手法: SOLUTION NMR PDB-2lyr: NOE-based 3D structure of the monomeric partially-folded intermediate of CylR2 at 259K (-14 Celsius degrees) 手法: SOLUTION NMR PDB-2lys: NOE-based 3D structure of the monomeric partially-folded intermediate of CylR2 at 257K (-16 Celsius degrees) 手法: SOLUTION NMR |
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由来 | ![](img/tx_bacteria.gif) enterococcus faecalis (乳酸球菌)
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キーワード | DNA BINDING PROTEIN / homodimer / CylR2 / NOE-based structure / protein folding / cold denaturation / cytolysin repressor 2 / helix-turn-helix / ensemble calculations / fast exchange dimer-monomer equlibrium / dimer dissociation / partially folded |
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