Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions
PDB-2dux: Crystal structure of human Aldose Reductase complexed with zopolrestat after 3 days soaking (3days_soaked_1) 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å
PDB-2duz: Human Aldose Reductase complexed with inhibitor zopolrestat after 3 days soaking (3days_soaked_2) 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å
PDB-2dv0: Human Aldose Reductase complexed with zopolrestat after 6 days soaking(6days_soaked_2) 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å
PDB-2fz8: Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking). 手法: X-RAY DIFFRACTION / 解像度: 1.48 Å
PDB-2fz9: Human Aldose Reductase complexed with inhibitor zopolrestat after six days soaking. 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å
PDB-2fzb: Human Aldose Reductase complexed with four tolrestat molecules at 1.5 A resolution. 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å
PDB-2fzd: Human aldose reductase complexed with tolrestat at 1.08 A resolution. 手法: X-RAY DIFFRACTION / 解像度: 1.08 Å
PDB-2hv5: Human Aldose Reductase complexed with inhibitor zopolrestat after three days soaking (3days_soaked_3) 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å
PDB-2hvn: Human Aldose Reductase-zopolrestat complex obtained by cocrystallisation after one day (1day_cocryst) 手法: X-RAY DIFFRACTION / 解像度: 1.58 Å
PDB-2hvo: Human Aldose Reductase-zopolrestat complex obtained by cocrystallisation (10days_cocryst) 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å