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-Structure paper
タイトル | Crystal structures of thrombin complexed to a novel series of synthetic inhibitors containing a 5,5-trans-lactone template. |
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ジャーナル・号・ページ | Biochemistry, Vol. 38, Page 7969-7977, Year 1999 |
掲載日 | 1999年5月26日 (構造データの登録日) |
![]() | Jhoti, H. / Cleasby, A. / Reid, S. / Thomas, P.J. / Weir, M. / Wonacott, A. |
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手法 | X線回折 |
解像度 | 2 - 2.2 Å |
構造データ | ![]() PDB-1qhr: ![]() PDB-1qj1: ![]() PDB-1qj6: ![]() PDB-1qj7: |
化合物 | ![]() ChemComp-157: ![]() ChemComp-HOH: ![]() ChemComp-166: ![]() ChemComp-167: ![]() ChemComp-GR1: |
由来 |
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![]() | BLOOD CLOTTING/HYDROLASE INHIBITOR / PROTEINASE / BLOOD COAGULATION / TRYPSIN LIKE PROTEINASE / COMPLEX (SERINE PROTEASE-INHIBITOR) / BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX / HYDROLASE/HYDROLASE INHIBITOR / BLOOD COAGULATION-INHIBITOR / PROTEASE-INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR COMPLEX / BLOOD COAGULATION-INHIBITOR COMPLEX / PROTEASE-INHIBITOR COMPLEX / HYDROLASE- HYDROLASE INHIBITOR COMPLEX |