[日本語] English
万見文献
- EMDB/PDB/SASBDBから引用されている文献のデータベース -

+
検索条件

キーワード
構造解析手法
著者・登録者
ジャーナル
IF

-
Structure paper

タイトルStructural Plasticity of Neurexin 1α: Implications for its Role as Synaptic Organizer.
ジャーナル・号・ページJ Mol Biol, Vol. 430, Issue 21, Page 4325-4343, Year 2018
掲載日2018年10月19日
著者Jianfang Liu / Anurag Misra / M V V V Sekhar Reddy / Mark Andrew White / Gang Ren / Gabby Rudenko /
PubMed 要旨α-Neurexins are synaptic organizing molecules implicated in neuropsychiatric disorders. They bind and arrange an array of different partners in the synaptic cleft. The extracellular region of ...α-Neurexins are synaptic organizing molecules implicated in neuropsychiatric disorders. They bind and arrange an array of different partners in the synaptic cleft. The extracellular region of neurexin 1α (n1α) contains six LNS domains (L1-L6) interspersed by three Egf-like repeats. N1α must encode highly evolved structure-function relationships in order to fit into the narrow confines of the synaptic cleft, and also recruit its large, membrane-bound partners. Internal molecular flexibility could provide a solution; however, it is challenging to delineate because currently no structural methods permit high-resolution structure determination of large, flexible, multi-domain protein molecules. To investigate the structural plasticity of n1α, in particular the conformation of domains that carry validated binding sites for different protein partners, we used a panel of structural techniques. Individual particle electron tomography revealed that the N-terminally and C-terminally tethered domains, L1 and L6, have a surprisingly limited range of conformational freedom with respect to the linear central core containing L2 through L5. A 2.8-Å crystal structure revealed an unexpected arrangement of the L2 and L3 domains. Small-angle X-ray scattering and electron tomography indicated that incorporation of the alternative splice insert SS6 relieves the restricted conformational freedom between L5 and L6, suggesting that SS6 may work as a molecular toggle. The architecture of n1α thus encodes a combination of rigid and flexibly tethered domains that are uniquely poised to work together to promote its organizing function in the synaptic cleft, and may permit allosterically regulated and/or concerted protein partner binding.
リンクJ Mol Biol / PubMed:30193986 / PubMed Central
手法EM (トモグラフィー) / X線回折
解像度2.84 - 16.5 Å
構造データ

EMDB-7639:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.08 Å

EMDB-7640:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.28 Å

EMDB-7641:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.5 Å

EMDB-7642:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.44 Å

EMDB-7643:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.74 Å

EMDB-7644:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 16.0 Å

EMDB-7645:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 16.27 Å

EMDB-7646:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.57 Å

EMDB-7647:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.55 Å

EMDB-7648:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 16.06 Å

EMDB-7649:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.74 Å

EMDB-7650:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.52 Å

EMDB-7651:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.58 Å

EMDB-7652:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.93 Å

EMDB-7653:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.11 Å

EMDB-7654:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.82 Å

EMDB-7655:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.72 Å

EMDB-7656:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.06 Å

EMDB-7657:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 15.22 Å

EMDB-7658:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 16.08 Å

EMDB-7659:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 021)
手法: EM (トモグラフィー) / 解像度: 15.96 Å

EMDB-7660:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 002)
手法: EM (トモグラフィー) / 解像度: 15.28 Å

EMDB-7661:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 003)
手法: EM (トモグラフィー) / 解像度: 15.5 Å

EMDB-7662:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 004)
手法: EM (トモグラフィー) / 解像度: 15.44 Å

EMDB-7663:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 005)
手法: EM (トモグラフィー) / 解像度: 15.74 Å

EMDB-7664:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 006)
手法: EM (トモグラフィー) / 解像度: 16.0 Å

EMDB-7665:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 007)
手法: EM (トモグラフィー) / 解像度: 16.27 Å

EMDB-7666:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 008)
手法: EM (トモグラフィー) / 解像度: 15.57 Å

EMDB-7667:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 009)
手法: EM (トモグラフィー) / 解像度: 15.55 Å

EMDB-7668:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 010)
手法: EM (トモグラフィー) / 解像度: 16.06 Å

EMDB-7669:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 011)
手法: EM (トモグラフィー) / 解像度: 15.74 Å

EMDB-7670:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 012)
手法: EM (トモグラフィー) / 解像度: 15.52 Å

EMDB-7671:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 013)
手法: EM (トモグラフィー) / 解像度: 15.28 Å

EMDB-7672:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 014)
手法: EM (トモグラフィー) / 解像度: 15.93 Å

EMDB-7673:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 015)
手法: EM (トモグラフィー) / 解像度: 15.11 Å

EMDB-7674:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 016)
手法: EM (トモグラフィー) / 解像度: 15.82 Å

EMDB-7675:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 017)
手法: EM (トモグラフィー) / 解像度: 15.72 Å

EMDB-7676:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 018)
手法: EM (トモグラフィー) / 解像度: 15.06 Å

EMDB-7677:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 019)
手法: EM (トモグラフィー) / 解像度: 15.22 Å

EMDB-7678:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 020)
手法: EM (トモグラフィー) / 解像度: 16.08 Å

EMDB-7679:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 022)
手法: EM (トモグラフィー) / 解像度: 14.75 Å

EMDB-7680:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 023)
手法: EM (トモグラフィー) / 解像度: 14.6 Å

EMDB-7681:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 024)
手法: EM (トモグラフィー) / 解像度: 15.5 Å

EMDB-7682:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 025)
手法: EM (トモグラフィー) / 解像度: 14.7 Å

EMDB-7683:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 026)
手法: EM (トモグラフィー) / 解像度: 14.92 Å

EMDB-7684:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 027)
手法: EM (トモグラフィー) / 解像度: 14.99 Å

EMDB-7685:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 028)
手法: EM (トモグラフィー) / 解像度: 15.77 Å

EMDB-7686:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 029)
手法: EM (トモグラフィー) / 解像度: 15.13 Å

EMDB-7687:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 030)
手法: EM (トモグラフィー) / 解像度: 14.95 Å

EMDB-7688:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 031)
手法: EM (トモグラフィー) / 解像度: 16.14 Å

EMDB-7689:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 032)
手法: EM (トモグラフィー) / 解像度: 14.92 Å

EMDB-7690:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 033)
手法: EM (トモグラフィー) / 解像度: 14.94 Å

EMDB-7691:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 034)
手法: EM (トモグラフィー) / 解像度: 15.53 Å

EMDB-7692:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 035)
手法: EM (トモグラフィー) / 解像度: 15.95 Å

EMDB-7693:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 036)
手法: EM (トモグラフィー) / 解像度: 15.6 Å

EMDB-7694:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 037)
手法: EM (トモグラフィー) / 解像度: 15.88 Å

EMDB-7695:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 038)
手法: EM (トモグラフィー) / 解像度: 15.09 Å

EMDB-7696:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 039)
手法: EM (トモグラフィー) / 解像度: 15.43 Å

EMDB-7697:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 040)
手法: EM (トモグラフィー) / 解像度: 14.95 Å

EMDB-7698:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 041)
手法: EM (トモグラフィー) / 解像度: 14.79 Å

EMDB-7699:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 042)
手法: EM (トモグラフィー) / 解像度: 16.05 Å

EMDB-7700:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 043)
手法: EM (トモグラフィー) / 解像度: 14.94 Å

EMDB-7701:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 044)
手法: EM (トモグラフィー) / 解像度: 15.84 Å

EMDB-7702:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 045)
手法: EM (トモグラフィー) / 解像度: 14.98 Å

EMDB-7703:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 046)
手法: EM (トモグラフィー) / 解像度: 15.48 Å

EMDB-7704:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 047)
手法: EM (トモグラフィー) / 解像度: 15.03 Å

EMDB-7705:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 048)
手法: EM (トモグラフィー) / 解像度: 15.4 Å

EMDB-7706:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 049)
手法: EM (トモグラフィー) / 解像度: 14.95 Å

EMDB-7707:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 050)
手法: EM (トモグラフィー) / 解像度: 15.08 Å

EMDB-7708:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 051)
手法: EM (トモグラフィー) / 解像度: 15.6 Å

EMDB-7709:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 052)
手法: EM (トモグラフィー) / 解像度: 15.12 Å

EMDB-7710:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 053)
手法: EM (トモグラフィー) / 解像度: 16.04 Å

EMDB-7711:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 054)
手法: EM (トモグラフィー) / 解像度: 15.69 Å

EMDB-7712:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 055)
手法: EM (トモグラフィー) / 解像度: 14.84 Å

EMDB-7713:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 056)
手法: EM (トモグラフィー) / 解像度: 14.86 Å

EMDB-7714:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 057)
手法: EM (トモグラフィー) / 解像度: 14.86 Å

EMDB-7715:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 058)
手法: EM (トモグラフィー) / 解像度: 15.04 Å

EMDB-7716:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 059)
手法: EM (トモグラフィー) / 解像度: 16.09 Å

EMDB-7717:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 060)
手法: EM (トモグラフィー) / 解像度: 15.26 Å

EMDB-7718:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 061)
手法: EM (トモグラフィー) / 解像度: 15.01 Å

EMDB-7719:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 062)
手法: EM (トモグラフィー) / 解像度: 15.39 Å

EMDB-7720:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 001)
手法: EM (トモグラフィー) / 解像度: 14.8 Å

EMDB-7721:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 064)
手法: EM (トモグラフィー) / 解像度: 14.7 Å

EMDB-7722:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 063)
手法: EM (トモグラフィー) / 解像度: 14.8 Å

EMDB-7723:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 065)
手法: EM (トモグラフィー) / 解像度: 15.1 Å

EMDB-7724:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 066)
手法: EM (トモグラフィー) / 解像度: 14.9 Å

EMDB-7725:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 067)
手法: EM (トモグラフィー) / 解像度: 15.6 Å

EMDB-7726:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 068)
手法: EM (トモグラフィー) / 解像度: 14.8 Å

EMDB-7727:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 069)
手法: EM (トモグラフィー) / 解像度: 16.2 Å

EMDB-7728:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 070)
手法: EM (トモグラフィー) / 解像度: 16.2 Å

EMDB-7729:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 071)
手法: EM (トモグラフィー) / 解像度: 14.4 Å

EMDB-7730:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 072)
手法: EM (トモグラフィー) / 解像度: 15.1 Å

EMDB-7731:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 073)
手法: EM (トモグラフィー) / 解像度: 15.8 Å

EMDB-7732:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 074)
手法: EM (トモグラフィー) / 解像度: 14.8 Å

EMDB-7733:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 075)
手法: EM (トモグラフィー) / 解像度: 14.9 Å

EMDB-7734:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 076)
手法: EM (トモグラフィー) / 解像度: 15.5 Å

EMDB-7735:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 077)
手法: EM (トモグラフィー) / 解像度: 15.5 Å

EMDB-7736:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 078)
手法: EM (トモグラフィー) / 解像度: 15.0 Å

EMDB-7737:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 079)
手法: EM (トモグラフィー) / 解像度: 14.9 Å

EMDB-7738:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 080)
手法: EM (トモグラフィー) / 解像度: 15.2 Å

EMDB-7739:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 081)
手法: EM (トモグラフィー) / 解像度: 15.9 Å

EMDB-7740:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 082)
手法: EM (トモグラフィー) / 解像度: 15.6 Å

EMDB-7741:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 083)
手法: EM (トモグラフィー) / 解像度: 15.3 Å

EMDB-7742:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 084)
手法: EM (トモグラフィー) / 解像度: 14.8 Å

EMDB-7743:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 085)
手法: EM (トモグラフィー) / 解像度: 15.8 Å

EMDB-7744:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 086)
手法: EM (トモグラフィー) / 解像度: 14.9 Å

EMDB-7745:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 087)
手法: EM (トモグラフィー) / 解像度: 14.8 Å

EMDB-7746:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 088)
手法: EM (トモグラフィー) / 解像度: 15.08 Å

EMDB-7747:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 089)
手法: EM (トモグラフィー) / 解像度: 15.9 Å

EMDB-7748:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 090)
手法: EM (トモグラフィー) / 解像度: 15.3 Å

EMDB-7749:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 091)
手法: EM (トモグラフィー) / 解像度: 15.6 Å

EMDB-7750:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 092)
手法: EM (トモグラフィー) / 解像度: 14.9 Å

EMDB-7751:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 093)
手法: EM (トモグラフィー) / 解像度: 16.5 Å

EMDB-7752:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 094)
手法: EM (トモグラフィー) / 解像度: 15.5 Å

EMDB-7753:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 095)
手法: EM (トモグラフィー) / 解像度: 14.8 Å

EMDB-7754:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 096)
手法: EM (トモグラフィー) / 解像度: 15.4 Å

EMDB-7755:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 097)
手法: EM (トモグラフィー) / 解像度: 16.1 Å

EMDB-7756:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 098)
手法: EM (トモグラフィー) / 解像度: 15.1 Å

EMDB-7757:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 099)
手法: EM (トモグラフィー) / 解像度: 15.4 Å

EMDB-7758:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 100)
手法: EM (トモグラフィー) / 解像度: 15.0 Å

EMDB-7759:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 101)
手法: EM (トモグラフィー) / 解像度: 15.0 Å

EMDB-7760:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 102)
手法: EM (トモグラフィー) / 解像度: 16.2 Å

EMDB-7761:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 103)
手法: EM (トモグラフィー) / 解像度: 15.2 Å

EMDB-7762:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 104)
手法: EM (トモグラフィー) / 解像度: 15.0 Å

EMDB-7763:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 105)
手法: EM (トモグラフィー) / 解像度: 15.1 Å

EMDB-7764:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 106)
手法: EM (トモグラフィー) / 解像度: 15.4 Å

EMDB-7765:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 107)
手法: EM (トモグラフィー) / 解像度: 15.1 Å

EMDB-7766:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 108)
手法: EM (トモグラフィー) / 解像度: 14.9 Å

EMDB-7767:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 109)
手法: EM (トモグラフィー) / 解像度: 16.0 Å

EMDB-7768:
Single-Molecule 3D Image of neurexin 1 alpha by Individual Particle Electron Tomography (No. 110)
手法: EM (トモグラフィー) / 解像度: 16.0 Å

PDB-6cw1:
Crystal structure of Neurexin-1 alpha ectodomain fragment, L2-L3
手法: X-RAY DIFFRACTION / 解像度: 2.84 Å

化合物

ChemComp-HOH:
WATER

由来
  • bos taurus (ウシ)
キーワードCELL ADHESION / LNS domain / Beta-Sandwich / Synapse

+
万見文献について

-
お知らせ

-
2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

-
2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbjlvh1.pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

+
2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

+
2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

+
2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

-
万見文献

EMDB/PDB/SASBDBから引用されている文献のデータベース

  • EMDB/PDB/SASBDBのエントリから引用されている文献のデータベースです
  • Pubmedのデータを利用しています

関連情報:EMDB / PDB / SASBDB / 万見 (Yorodumi) / EMN文献 / 新しいEM Navigatorと万見の変更点

他の情報も見る