+検索条件
-Structure paper
タイトル | Conformational variability of cyanobacterial ChlI, the AAA+ motor of magnesium chelatase involved in chlorophyll biosynthesis. |
---|---|
ジャーナル・号・ページ | mBio, Vol. 14, Issue 5, Page e0189323, Year 2023 |
掲載日 | 2023年9月22日 |
![]() | Dmitry Shvarev / Alischa Ira Scholz / Arne Moeller / ![]() |
PubMed 要旨 | Photosynthesis is an essential life process that relies on chlorophyll. In photosynthetic organisms, chlorophyll synthesis involves multiple steps and depends on magnesium chelatase. This enzyme ...Photosynthesis is an essential life process that relies on chlorophyll. In photosynthetic organisms, chlorophyll synthesis involves multiple steps and depends on magnesium chelatase. This enzyme complex is responsible for inserting magnesium into the chlorophyll precursor, but the molecular mechanism of this process is not fully understood. By using cryogenic electron microscopy and conducting functional analyses, we have discovered that the motor subunit ChlI of magnesium chelatase undergoes conformational changes in the presence of ATP. Our findings offer new insights into how energy is transferred from ChlI to the other components of magnesium chelatase. This information significantly contributes to our understanding of the initial step in chlorophyll biosynthesis and lays the foundation for future studies on the entire process of chlorophyll production. |
![]() | ![]() ![]() ![]() |
手法 | EM (単粒子) |
解像度 | 3.8 - 4.9 Å |
構造データ | EMDB-17151, PDB-8osf: EMDB-17152, PDB-8osg: EMDB-17153, PDB-8osh: |
化合物 | ![]() ChemComp-ATP: ![]() ChemComp-MG: ![]() ChemComp-ADP: |
由来 |
|
![]() | PHOTOSYNTHESIS / AAA+ / Magnesium Chelatase / Cyanobacteria |