EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Fragment screening for a protein-protein interaction inhibitor to WDR5.
ジャーナル・号・ページ	Struct Dyn., Vol. 6, Page 064701-064701, Year 2019
掲載日	2019年6月24日 (構造データの登録日)
著者	Dennis, M.L. / Morrow, B.J. / Dolezal, O. / Cuzzupe, A.N. / Stupple, A.E. / Newman, J. / Bentley, J. / Hattarki, M. / Nuttall, S.D. / Foitzik, R.C. ...Dennis, M.L. / Morrow, B.J. / Dolezal, O. / Cuzzupe, A.N. / Stupple, A.E. / Newman, J. / Bentley, J. / Hattarki, M. / Nuttall, S.D. / Foitzik, R.C. / Street, I.P. / Stupple, P.A. / Monahan, B.J. / Peat, T.S.
リンク	Struct Dyn. / PubMed:31768400
手法	X線回折
解像度	1.5 - 2.45 Å
構造データ	PDB-6pg3: WDR5delta23 bound to (2-butyl-1H-imidazol-4-yl)methanol 手法: X-RAY DIFFRACTION / 解像度: 2.04 Å PDB-6pg4: WDR5delta32 bound to (2-methyl-1H-imidazol-4-yl)methanol 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-6pg5: WDR5delta32 bound to benzyl (4-(5-(hydroxymethyl)-1H-imidazol-2-yl)butyl)carbamate 手法: X-RAY DIFFRACTION / 解像度: 1.99 Å PDB-6pg6: WDR5delta23 bound to N-(4-(5-(hydroxymethyl)-1H-imidazol-2-yl)butyl)acetamide 手法: X-RAY DIFFRACTION / 解像度: 1.68 Å PDB-6pg7: WDR5delta32 bound to (2-(3-methoxy-3-phenylpropyl)-1H-imidazol-4-yl)methanol 手法: X-RAY DIFFRACTION / 解像度: 2.45 Å PDB-6pg8: WDR5delta23 bound to (2-(3-phenylpropyl)-1H-imidazol-4-yl)methanol 手法: X-RAY DIFFRACTION / 解像度: 1.67 Å PDB-6pg9: WDR5delta23 bound to N-(4-(5-(hydroxymethyl)-1H-imidazol-2-yl)butyl)benzamide 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-6pga: WDR5delta32 bound to methyl (4-(4-(hydroxymethyl)-1H-imidazol-2-yl)butyl)carbamate 手法: X-RAY DIFFRACTION / 解像度: 2.45 Å PDB-6pgb: WDR5delta32 bound to N-(4-(5-(hydroxymethyl)-1H-imidazol-2-yl)butyl)-2-phenylacetamide 手法: X-RAY DIFFRACTION / 解像度: 1.73 Å PDB-6pgc: WDR5delta32 bound to methyl benzyl(4-(4-(hydroxymethyl)-1H-imidazol-2-yl)butyl)carbamate 手法: X-RAY DIFFRACTION / 解像度: 1.81 Å PDB-6pgd: WDR5delta32 bound to peptidomimetic 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-6pge: WDR5delta32 bound to ethyl 3-(4-(hydroxymethyl)-1H-imidazol-2-yl)propanoate 手法: X-RAY DIFFRACTION / 解像度: 1.76 Å PDB-6pgf: WDR5delta32 bound to N-(4-(4-(hydroxymethyl)-1H-imidazol-2-yl)butyl)acrylamide 手法: X-RAY DIFFRACTION / 解像度: 1.54 Å
化合物	ChemComp-OHJ: (2-butyl-1H-imidazol-4-yl)methanol / 2-ブチル-1H-イミダゾ-ル-5-メタノ-ル ChemComp-HOH: WATER / 水 ChemComp-OHG: (2-methyl-1H-imidazol-4-yl)methanol / 2-メチル-1H-イミダゾ-ル-4-メタノ-ル ChemComp-SO4: SULFATE ION / 硫酸ジアニオン / 硫酸塩 ChemComp-OHV: benzyl {4-[5-(hydroxymethyl)-1H-imidazol-2-yl]butyl}carbamate ChemComp-OH7: N-{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}acetamide ChemComp-CL: Unknown entry / クロリド / 塩化物 ChemComp-OH4: {2-[(3S)-3-methoxy-3-phenylpropyl]-1H-imidazol-4-yl}methanol ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル / ジエチレングリコール ChemComp-OGY: [2-(3-phenylpropyl)-1H-imidazol-4-yl]methanol ChemComp-OH1: N-{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}benzamide ChemComp-OGM: methyl {4-[5-(hydroxymethyl)-1H-imidazol-2-yl]butyl}carbamate ChemComp-OJG: N-{4-[5-(hydroxymethyl)-1H-imidazol-2-yl]butyl}-2-phenylacetamide ChemComp-OJJ: methyl benzyl{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}carbamate ChemComp-OK4: N-acetyl-L-alanyl-5-[5-(hydroxymethyl)-1H-imidazol-2-yl]-L-norvalyl-L-valinamide ChemComp-OJM: ethyl 3-[4-(hydroxymethyl)-1H-imidazol-2-yl]propanoate ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル / エチレングリコール ChemComp-OJP: N-{4-[4-(hydroxymethyl)-1H-imidazol-2-yl]butyl}prop-2-enamide
由来	homo sapiens (ヒト)
キーワード	PROTEIN BINDING/Inhibitor / Inhibitor / Scaffolding Protein (足場タンパク質) / B-propellor / Chromatin regulator / PROTEIN BINDING (タンパク質) / PROTEIN BINDING-Inhibitor complex