EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
ジャーナル・号・ページ	J. Am. Chem. Soc., Vol. 137, Page 7835-7842, Year 2015
掲載日	2015年2月12日 (構造データの登録日)
著者	Huber, E.M. / de Bruin, G. / Heinemeyer, W. / Paniagua Soriano, G. / Overkleeft, H.S. / Groll, M.
リンク	J. Am. Chem. Soc. / PubMed:26020686
手法	X線回折
解像度	2.4 - 2.9 Å
構造データ	PDB-4y69: Yeast 20S proteasome in complex with Ac-PAD-ep 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-4y6a: Yeast 20S proteasome beta2-H114D mutant in complex with Ac-PAD-ep 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-4y6v: Yeast 20S proteasome in complex with Ac-PAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4y6z: Yeast 20S proteasome in complex with Ac-PAL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4y70: Yeast 20S proteasome in complex with Ac-LAV-ep 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-4y74: Yeast 20S proteasome in complex with Ac-LAL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4y75: Yeast 20S proteasome in complex with Ac-PAF-ep 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4y77: Yeast 20S proteasome in complex with Ac-LAF-ep 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-4y78: Yeast 20S proteasome in complex with Ac-LAD-ep 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4y7w: Yeast 20S proteasome in complex with Ac-LAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-4y7x: Yeast 20S proteasome in complex with Ac-PAA-ep 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-4y7y: Yeast 20S proteasome in complex with Ac-LAA-ep 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-4y80: Yeast 20S proteasome in complex with Ac-LAI-ep 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-4y81: Yeast 20S proteasome in complex with Ac-PAY-ep 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4y82: Yeast 20S proteasome in complex with Ac-LAY-ep 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4y84: Yeast 20S proteasome in complex with N3-A(4,4-F2P)nLL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4y8g: Yeast 20S proteasome in complex with N3-APnLL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-4y8h: Yeast 20S proteasome in complex with N3-APAL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-4y8i: Yeast 20S proteasome in complex with Ac-PLL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-4y8j: Yeast 20S proteasome in complex with Ac-LLL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4y8k: Yeast 20S proteasome in complex with H-APLL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-4y8l: Yeast 20S proteasome in complex with Ac-APLL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-4y8m: Yeast 20S proteasome beta7-delta7_Cter mutant 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4y8n: Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-4y8o: Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAF-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4y8p: Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAL-ep 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4y8q: Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAY-ep 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-4y8r: Yeast 20S proteasome beta2-H116D mutant 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4y8s: Yeast 20S proteasome beta2-H116D mutant in complex with Ac-LAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4y8t: Yeast 20S proteasome beta2-H116D mutant in complex with Ac-PAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4y8u: Yeast 20S proteasome beta2-H116D mutant in complex with Ac-PAD-ep 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-4y9y: Yeast 20S proteasome beta2-H116E mutant 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4y9z: Yeast 20S proteasome beta2-H116E mutant in complex with Ac-LAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4ya0: Yeast 20S proteasome beta2-H116E mutant in complex with Ac-PAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4ya1: Yeast 20S proteasome beta2-H116N mutant 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-4ya2: Yeast 20S proteasome beta2-H116N mutant in complex with Ac-LAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4ya3: Yeast 20S proteasome beta2-H116N mutant in complex with Ac-PAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4ya4: Yeast 20S proteasome beta2-H114D mutant 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-4ya5: Yeast 20S proteasome beta2-H114D mutant in complex with Ac-PAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-4ya7: Yeast 20S proteasome beta2-H114D mutant in complex with Ac-LAE-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-4ya9: Yeast 20S proteasome beta2-H114D mutant in complex with Ac-LAD-ep 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å
化合物	ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-CL: Unknown entry / クロリド / 塩化物 ChemComp-HOH: WATER / 水 ChemComp-MES: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID / 2-モルホリノエタンスルホン酸 / pH緩衝剤YM / MES (緩衝剤) ChemComp-K*: Unknown entry / カリウムカチオン
由来	saccharomyces cerevisiae (strain atcc 204508 / s288c) (パン酵母) synthetic construct (人工物) saccharomyces cerevisiae (パン酵母) saccharomyces cerevisiae s288c (パン酵母) scientific construct (人工物)
キーワード	HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR complex / Proteasome (プロテアソーム) / Inhibitor / Binding Analysis / Mutant (ミュータント (人類)) / HYDROLASE (加水分解酵素)