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Structure paper

TitleA fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants
Journal, issue, pagesTo Be Published
Publish dateJan 29, 2024 (structure data deposition date)
AuthorsFairhead, M. / Strain-Damerell, C. / Ye, M. / Mackinnon, S.R. / Pinkas, D. / MacLean, E.M. / Koekemoer, L. / Damerell, D. / Krojer, T. / Yue, W. ...Fairhead, M. / Strain-Damerell, C. / Ye, M. / Mackinnon, S.R. / Pinkas, D. / MacLean, E.M. / Koekemoer, L. / Damerell, D. / Krojer, T. / Yue, W. / Burgess-Brown, N. / Marsden, B. / von Delft, F.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.19 - 2.21 Å
Structure data

PDB-8ru1:
Chromatin remodeling regulator CECR2 with in crystallo disulfide bond
Method: X-RAY DIFFRACTION / Resolution: 1.66 Å

PDB-8ru5:
ATPase family AAA domain containing 2 with crystallization epitope mutations V1022R:Q1027E
Method: X-RAY DIFFRACTION / Resolution: 1.36 Å

PDB-9gdk:
Jumonji domain-containing protein 1C with crystallization epitope mutations L2440Y:G2444H
Method: X-RAY DIFFRACTION / Resolution: 1.78 Å

PDB-9gh3:
pleckstrin homology domain interacting protein with crystallization epitope mutations L1408N:R1409E
Method: X-RAY DIFFRACTION / Resolution: 1.19 Å

PDB-9gii:
Jumonji domain-containing protein 2A with crystallization epitope mutation R913A
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-9gle:
Jumonji domain-containing protein 2A with crystallization epitope mutations A91T:T93S
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-9gp1:
Jumonji domain-containing protein 2A with crystallization epitope mutatios K330R:A334E
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

PDB-9gp4:
Jumonji domain-containing protein 2A with crystallization epitope mutations Q953E:A958D
Method: X-RAY DIFFRACTION / Resolution: 1.59 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-SO4:
SULFATE ION

ChemComp-NI:
NICKEL (II) ION

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Crystal Epitopes / Bromodomain / Structural Genomics / Structural Genomics Consortium / SGC / SIGNALING PROTEIN / PROTEIN BINDING / OXIDOREDUCTASE / Jumonji domain

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