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TitleMechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine.
Journal, issue, pagesNat Commun, Vol. 16, Page 2898-2898, Year 2025
Publish dateApr 20, 2024 (structure data deposition date)
AuthorsBrangulis, K. / Malfetano, J. / Marcinkiewicz, A.L. / Wang, A. / Chen, Y.L. / Lee, J. / Liu, Z. / Yang, X. / Strych, U. / Tupina, D. ...Brangulis, K. / Malfetano, J. / Marcinkiewicz, A.L. / Wang, A. / Chen, Y.L. / Lee, J. / Liu, Z. / Yang, X. / Strych, U. / Tupina, D. / Akopjana, I. / Bottazzi, M.E. / Pal, U. / Hsieh, C.L. / Chen, W.H. / Lin, Y.P.
External linksNat Commun / PubMed:40189575
MethodsX-ray diffraction
Resolution1.9 - 1.95 Å
Structure data

PDB-9f1v:
Crystal structure of Borrelia burgdorferi CspZ-YA
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-9f21:
Crystal structure of Borrelia burgdorferi CspZ-YACS
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • borreliella burgdorferi b31 (bacteria)
KeywordsIMMUNE SYSTEM / complement-binding protein; Lyme disease; borreliosis / complement-binding protein; Lyme disease; borreliosis.

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