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TitleStructure defining of ultrapotent neutralizing nanobodies against MERS-CoV with novel epitopes on receptor binding domain.
Journal, issue, pagesPlos Pathog., Vol. 20, Page e1012438-e1012438, Year 2024
Publish dateMar 22, 2024 (structure data deposition date)
AuthorsMa, S. / Zhang, D. / Wang, Q. / Zhu, L. / Wu, X. / Ye, S. / Wang, Y.
External linksPlos Pathog. / PubMed:39141662
MethodsX-ray diffraction
Resolution1.99 - 2.76 Å
Structure data

PDB-8ysf:
MERS-CoV RBD in complex with nanobody Nb9
Method: X-RAY DIFFRACTION / Resolution: 2.76 Å

PDB-8ysh:
MERS-CoV RBD in complex with nanobody Nb14
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • middle east respiratory syndrome-related coronavirus
  • vicugna pacos (alpaca)
KeywordsVIRAL PROTEIN / MERS-CoV nanobody Nb9 / MERS-CoV nanobody Nb14

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