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Structure paper

TitleStructural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Journal, issue, pagesAdv Sci, Vol. 11, Page e2309891-e2309891, Year 2024
Publish dateNov 22, 2023 (structure data deposition date)
AuthorsVianney, Y.M. / Dierks, D. / Weisz, K.
External linksAdv Sci / PubMed:38477454
MethodsNMR (solution)
Structure data

PDB-8r6d:
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology
Method: SOLUTION NMR

PDB-8r6g:
A quadruplex-duplex hybrid with a three-layered chair G-quadruplex topology
Method: SOLUTION NMR

PDB-8r6h:
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology complexed with Phen-DC3
Method: SOLUTION NMR

Chemicals

ChemComp-PQ3:
N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide

Source
  • synthetic construct (others)
KeywordsDNA / (3+1) hybrid / hybrid-2 / G-quadruplex / Quadruplex-duplex hybrid / (2+2) antiparallel topology / intercalation / Phen-DC3

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