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-Structure paper
Title | Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection. |
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Journal, issue, pages | J. Med. Chem., Vol. 66, Page 4253-4270, Year 2023 |
Publish date | Jan 30, 2023 (structure data deposition date) |
![]() | Zhang, W. / Guo, L. / Liu, H. / Wu, G. / Shi, H. / Zhou, M. / Zhang, Z. / Kou, B. / Hu, T. / Zhou, Z. ...Zhang, W. / Guo, L. / Liu, H. / Wu, G. / Shi, H. / Zhou, M. / Zhang, Z. / Kou, B. / Hu, T. / Zhou, Z. / Xu, Z. / Zhou, X. / Zhou, Y. / Tian, X. / Yang, G. / Young, J.A.T. / Qiu, H. / Ottaviani, G. / Xie, J. / Mayweg, A.V. / Shen, H.C. / Zhu, W. |
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Methods | X-ray diffraction |
Resolution | 1.6 Å |
Structure data | ![]() PDB-8i71: |
Chemicals | ![]() ChemComp-CL: ![]() ChemComp-IPA: ![]() ChemComp-GOL: ![]() ChemComp-OTI: ![]() ChemComp-DMS: ![]() ChemComp-HOH: |
Source |
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![]() | VIRAL PROTEIN / capsid assembly inhibitor / ANTIVIRAL PROTEIN |