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TitleInvestigation of AMA Synthase from Pyrenophora teres f. teres 0-1 for the Synthesis of Aspergillomarasmine A Analogues and Non-Canonical Amino Acids
Journal, issue, pagesAdv. Synth. Catal., Vol. 366, Page 5160-5170, Year 2024
Publish dateOct 10, 2022 (structure data deposition date)
AuthorsZhu, Z. / Ma, Y. / Xie, X. / Wang, Z. / Han, L. / Song, J. / Liang, Y. / Poelarends, G.J. / Chen, Y. / Lu, M. / Zhang, J.
External linksAdv. Synth. Catal. / Search PubMed
MethodsX-ray diffraction
Resolution2.22 - 2.3 Å
Structure data

PDB-8h4h:
The apo structure of Aspergillomarasmine A synthetase
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-8h4q:
Aspergillomarasmine A biosynthese complex with OPS
Method: X-RAY DIFFRACTION / Resolution: 2.22 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-P1T:
2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID

Source
  • pyrenophora teres f. teres 0-1 (fungus)
KeywordsBIOSYNTHETIC PROTEIN / synthase / PLP-dependent enzyme / Aspergillomarasmine A biosynthese

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