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-Structure paper
Title | Characterization of a Potent and Orally Bioavailable Lys-Covalent Inhibitor of Apoptosis Protein (IAP) Antagonist. |
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Journal, issue, pages | J. Med. Chem., Vol. 66, Page 8159-8169, Year 2023 |
Publish date | Mar 9, 2023 (structure data deposition date) |
Authors | Udompholkul, P. / Garza-Granados, A. / Alboreggia, G. / Baggio, C. / McGuire, J. / Pegan, S.D. / Pellecchia, M. |
External links | J. Med. Chem. / PubMed:37262387 |
Methods | X-ray diffraction |
Resolution | 1.75 Å |
Structure data | PDB-8gh7: |
Chemicals | ChemComp-ZN: ChemComp-7PE: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN/INHIBITOR / BIR Domain / protein-ligand complex / BIR3 inhibitor / zinc finger motif / SIGNALING PROTEIN / SIGNALING PROTEIN-INHIBITOR complex |