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TitlePreclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate.
Journal, issue, pagesMol Ther Oncolytics, Vol. 31, Page 100726-100726, Year 2023
Publish dateJan 10, 2023 (structure data deposition date)
AuthorsSun, Z. / Chu, X. / Adams, C. / Ilina, T.V. / Guerrero, M. / Lin, G. / Chen, C. / Jelev, D. / Ishima, R. / Li, W. ...Sun, Z. / Chu, X. / Adams, C. / Ilina, T.V. / Guerrero, M. / Lin, G. / Chen, C. / Jelev, D. / Ishima, R. / Li, W. / Mellors, J.W. / Calero, G. / Dimitrov, D.S.
External linksMol Ther Oncolytics / PubMed:37771390
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-8fsl:
Human Mesothelin bound to a neutralizing VH domain antibody
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Source
  • escherichia coli (E. coli)
  • insect expression vector pbluebacmsgca1his (others)
KeywordsANTITUMOR PROTEIN / Mesothelin VH

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